Nanoparticle-mediated combination therapy: two-in-one approach for cancer

S Gurunathan, MH Kang, M Qasim, JH Kim - International journal of …, 2018 - mdpi.com
Cancer represents a group of heterogeneous diseases characterized by uncontrolled
growth and spread of abnormal cells, ultimately leading to death. Nanomedicine plays a …

Recent advances in TPGS-based nanoparticles of docetaxel for improved chemotherapy

H Choudhury, B Gorain, M Pandey, SA Kumbhar… - International journal of …, 2017 - Elsevier
Docetaxel (DTX) is one of the important antitumor drugs, being used in several common
chemotherapies to control leading cancer types. Severe toxicities of the DTX are prominent …

Preparation and characterization of docetaxel-PLGA nanoparticles coated with folic acid-chitosan conjugate for cancer treatment

NK Al-Nemrawi, RM Altawabeyeh… - Journal of Pharmaceutical …, 2022 - Elsevier
The conjugation of chitosan (CS) and folic acid (FA) was prepared and used to coat PLGA
nanoparticles (NPs) that are loaded with Docetaxel (DTX) to target cancer cells that have …

Encapsulation of biophenolic phytochemical EGCG within lipid nanoparticles enhances its stability and cytotoxicity against cancer

R Radhakrishnan, H Kulhari, D Pooja, S Gudem… - Chemistry and physics …, 2016 - Elsevier
Epigallocatechin gallate (EGCG), a green tea polyphenolic catechin, has been known to
possess a variety of beneficial biological activities. The in-vitro anti-cancer activity of EGCG …

Development of antioxidant and antimicrobial packaging films based on chitosan, D-α-tocopheryl polyethylene glycol 1000 succinate and silicon dioxide nanoparticles

F Bi, X Zhang, J Liu, H Yong, L Gao, J Liu - Food Packaging and Shelf Life, 2020 - Elsevier
Antioxidant and antimicrobial packaging were developed by adding D-α-tocopheryl
polyethylene glycol 1000 succinate (TPGS) and/or silicon dioxide nanoparticles (nano-SiO …

A multifunctional nanoplatform for cancer chemo-photothermal synergistic therapy and overcoming multidrug resistance

Y Peng, J Nie, W Cheng, G Liu, D Zhu, L Zhang… - Biomaterials …, 2018 - pubs.rsc.org
The integration of various therapy strategies into a single nanoplatform for synergistic cancer
treatment has presented a great prospect. Herein, docetaxel (DTX)-loaded poly lactic-co …

An effective strategy for development of docetaxel encapsulated gold nanoformulations for treatment of prostate cancer

S Thambiraj, R Vijayalakshmi, D Ravi Shankaran - Scientific Reports, 2021 - nature.com
Nanoformulation based drug delivery is one of the most important research areas in the field
of nanomedicine, which provides promising alternatives to the limitations of conventional …

A safe, simple and efficient doxorubicin prodrug hybrid micelle for overcoming tumor multidrug resistance and targeting delivery

Y Bao, M Yin, X Hu, X Zhuang, Y Sun, Y Guo… - Journal of Controlled …, 2016 - Elsevier
A pH-sensitive prodrug, TPGS-CH double bondN-DOX, was introduced by conjugating
anticancer drug, doxorubicin (DOX), onto d-α-tocopherol polyethylene glycol 1000 succinate …

Genistein encapsulated inulin-stearic acid bioconjugate nanoparticles: Formulation development, characterization and anticancer activity

AK Jangid, R Solanki, S Patel, D Pooja… - International Journal of …, 2022 - Elsevier
Achieving controlled and site-specific delivery of hydrophobic drugs in the colon
environment is a major challenge. The primary goal of this research was to synthesize inulin …

Improving anticancer activity of chrysin using tumor microenvironment pH-responsive and self-assembled nanoparticles

AK Jangid, R Solanki, S Patel, K Medicherla… - ACS …, 2022 - ACS Publications
Chrysin is a natural bioactive compound with potential biological activities. However,
unfavorable physicochemical properties of native chrysin make it difficult to achieve good …