RNA-binding proteins (RBPs) play a critical role in the regulation of various RNA processes,
including splicing, cleavage and polyadenylation, transport, translation and degradation of …

Senescent cells secrete a combination of factors collectively known as the senescence-
associated secretory phenotype (SASP). The SASP reinforces senescence and activates an …

Long ignored as a vestigial remnant of cytokinesis, the mammalian midbody (MB) is
released post-abscission inside large extracellular vesicles called MB remnants (MBRs) …

Cancer is a complicated transformational progression that fiercely changes the appearance
of cell physiology as well as cells' relations with adjacent tissues. Developing an oncogenic …

ZFP36 family members include ZFP36, ZFP36L1, and ZFP36L2, which belong to CCCH-
type zinc finger proteins with two tandem zinc finger (TZF) regions. Whether ZFP36L1 and …

In animals with germ plasm, specification of the germline involves 'germ granules',
cytoplasmic condensates that enrich maternal transcripts in the germline founder cells. In …

Dermal fibroblasts are strategically positioned underneath the basal epidermis layer to
support keratinocyte proliferation and extracellular matrix production. In inflammatory …

Abstract Adenylate-uridylate (AU)-rich elements (AREs) are sequence instability elements
that are known to be located in the 3′ untranslated regions (UTR) in thousands of human …

The muscleblind-like (MBNL) genes encode alternative splicing factors that are essential for
the postnatal development of multiple tissues, and the inhibition of MBNL activity by toxic C …

The role of inflammation in skeletal muscle adaptation to exercise is complex and has hardly
been elucidated so far. While the acute inflammatory response to exercise seems to promote …