Integrins are considered the main cell-adhesion transmembrane receptors that play
multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in …

Antiplatelet drugs, such as aspirin, P2Y12 antagonists, and glycoprotein (GP) IIb/IIIa
inhibitors, have proved to be successful in reducing the morbidity and mortality associated …

It is important that the medical profession play a significant role in critically evaluating the
use of diagnostic procedures and therapies as they are introduced and tested in the …

The ACC/AHA Task Force on Practice Guidelines was formed to make recommendations
regarding the diagnosis and treatment of patients with known or suspected cardiovascular …

How ligand binding alters integrin conformation in outside-in signaling, and how inside-out
signals alter integrin affinity for ligand, have been mysterious. We address this with electron …

2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the
Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction …

Conclusions...... 1025 V. Hospital Discharge and Post–Hospital Discharge Care...... 1025 A.
Medical Regimen...... 1026 1. Long-Term Medical Therapy...... 1026 B. Postdischarge Follow …

For new or updated text, view the 2011 Focused Update. Text supporting unchanged
recommendations has not been updated. The ACC/AHA Task Force on Practice Guidelines …

This article discusses platelet active drugs as part of the Seventh American College of Chest
Physicians Conference on Antithrombotic and Thrombolytic Therapy: Evidence-Based …

The role of aspirin and other platelet-active drugs in the treatment and prevention of
atherothrombosis has been reviewed recently by the Sixth American College of Chest …