Molecular mechanosensors in osteocytes

L Qin, W Liu, H Cao, G Xiao - Bone research, 2020 - nature.com
Osteocytes, the most abundant and long-lived cells in bone, are the master regulators of
bone remodeling. In addition to their functions in endocrine regulation and calcium and …

Biomimetic approaches in bone tissue engineering: Integrating biological and physicomechanical strategies

MA Fernandez-Yague, SA Abbah, L McNamara… - Advanced drug delivery …, 2015 - Elsevier
The development of responsive biomaterials capable of demonstrating modulated function
in response to dynamic physiological and mechanical changes in vivo remains an important …

[PDF][PDF] Mechanical loading and how it affects bone cells: the role of the osteocyte cytoskeleton in maintaining our skeleton

J Klein-Nulend, RG Bacabac, AD Bakker - Eur Cell Mater, 2012 - Citeseer
Lack of physical activity causes bone loss and fractures not only in elderly people, but also
in bedridden patients or otherwise inactive youth. This is fast becoming one of the most …

Review on cell mechanics: experimental and modeling approaches

ML Rodriguez, PJ McGarry… - Applied …, 2013 - asmedigitalcollection.asme.org
The interplay between the mechanical properties of cells and the forces that they produce
internally or that are externally applied to them play an important role in maintaining the …

Estimates of natural frequencies for nuclear vibration, and an assessment of the feasibility of selective ultrasound ablation of cancer cells

B Qi, H Zhang, J Zhu, M Wang, C Ma, GM Genin… - Journal of the …, 2024 - Elsevier
Selective ablation of cancer cells by ultrasound would be transformative for cancer therapy,
but has not yet been possible. A key challenge is that cancerous and non-cancerous cells …

Tunnels in the rock: Dynamics of osteocyte morphogenesis

Y Moharrer, JD Boerckel - Bone, 2021 - Elsevier
Osteocytes are dynamic, bone matrix-remodeling cells that form an intricate network of
interconnected projections through the bone matrix, called the lacunar-canalicular system …

Bone fracture healing: perspectives according to molecular basis

IN Camal Ruggieri, AM Cícero, JPM Issa… - Journal of bone and …, 2021 - Springer
Fractures have a great impact on health all around the world and with fracture healing
optimization; this problem could be resolved partially. To make a practical contribution to this …

[图书][B] Embryogenesis explained

NK Gordon, R Gordon - 2016 - books.google.com
The greatest mystery of life is how a single fertilized egg develops into a fully functioning,
sometimes conscious multicellular organism. Embryogenesis Explained offers a new theory …

Effects of immediate loading directionality on the mechanical sensing protein PIEZO1 expression and early-stage healing process of peri-implant bone

C Mao, W Yu, G Li, Z Xu, Y Gong, M Jin… - BioMedical Engineering …, 2024 - Springer
Background The reduced treatment time of dental implants with immediate loading protocol
is an appealing solution for dentists and patients. However, there remains a significant risk …

[HTML][HTML] A comprehensive framework for multibody system analysis with clustered cables: examples of tensegrity structures

Z Kan, N Song, H Peng, B Chen, X Song - International Journal of Solids …, 2021 - Elsevier
Structures with clustered cables are widespread in many engineering applications. Most
existing works involving clustered cables are based on a finite element formulation and do …