Covering: 2012. Previous review: Nat. Prod. Rep., 2013, 30, 237–323. This review covers
the literature published in 2012 for marine natural products, with 1035 citations (673 for the …

The peer-reviewed marine pharmacology literature from 2012 to 2013 was systematically
reviewed, consistent with the 1998–2011 reviews of this series. Marine pharmacology …

Natural products are primal and have been a driver in the evolution of organic chemistry and
ultimately in science. The chemical structures obtained from marine organisms are diverse …

We investigated the three soft corals Sarcophyton stellatum, Capnella fungiformis and
Lobophytum crassum and the sponge Pseudoceratina arabica, which have been collected …

The modulation of FXR receptor remains an attractive area in drug discovery to develop
novel therapeutic opportunities for liver and metabolic disorders. Despite the large variety of …

Abstract A new 9, 11-secosteroid, 25 (26)-dehydrosarcomilasterol (1), two new
polyhydroxylated steroids, 7α-hydroxy-crassarosterol A (2) and 11-acetoxy-7α-hydroxy …

In the recent years, bile acid receptors FXR and GPBAR1 have attracted the interest of
scientific community and companies, as they proved promising targets for the treatment of …

Nuclear receptors (NRs) are a large family of evolutionarily conserved and ligand-regulated
transcription factors. The farnesoid X receptor (FXR) and the pregnane X receptor (PXR) are …

Two new steroids,(2β, 3β, 4α, 5α, 8β)-4-methylergost-24 (28)-ene-2, 3, 8-triol (1) and (3β,
7α)-24-methyl-7-hydroperoxycholest-5, 24 (28)-diene-3-ol (2), together with 13 known …

Metabolic syndrome (MetS) has been a growing public health concern worldwide without
specific medicine. Through summarizing the chemical structure type and effect mechanisms …