Diabetic foot ulcers (DFUs) are a devastating complication for diabetic patients that have
debilitating effects and can ultimately lead to limb amputation. Healthy wounds progress …

Abstract N6-methyladenosine (m6A) modification is a class of epitope modifications that has
received significant attention in recent years, particularly in relation to its role in various …

Diabetic kidney disease (DKD) poses a threat to people's health. The current treatments only
provide partial relief of symptoms. Therefore, seeking a promising therapeutic medication for …

There is a great interest nowadays, in the research for wound dressings that promote the
healing process of skin injuries. These dressings protect the wounds from infections while …

Diabetic bone defect repair is one of the major challenges in clinic, because the pathological
microenvironments such as hyperglycemia, oxidative stress, and inflammation exist in the …

Abstract Background Tibial Cortex Transverse Transport (TTT) has been demonstrated to be
an effective treatment for unilateral diabetic foot ulcers (UDFUs). However, this retrospective …

Objective Traditional Chinese medicine Polygonum cuspidatum (PC) has significant effects
on reducing pain. In this study, we investigated the analgesic effects of the alcohol extract of …

PTP1B plays an important role as a key negative regulator of tyrosine phosphorylation
associated with insulin receptor signaling in the therapy for diabetes and obesity. In this …

Chronic wound healing impairment is a significant complication in diabetes. Hydrogels that
maintain wound moisture and enable sustained drug release have become prominent for …

Extracellular vesicles (EVs) are important cell-to-cell communication mediators. This paper
focuses on the regulatory role of tumor-derived EVs on macrophages. It aims to investigate …