We provide a comprehensive classification of the proteoglycan gene families and respective
protein cores. This updated nomenclature is based on three criteria: Cellular and subcellular …

Mesangial cells are stromal cells that are important for kidney glomerular homeostasis and
the glomerular response to injury. A growing body of evidence demonstrates that …

The basic unit of kidney function is the nephron. In the mouse, around 14,000 nephrons form
in a 10-day period extending into early neonatal life, while the human fetus forms the adult …

Cellular interactions among nephron, interstitial, and collecting duct progenitors drive
mammalian kidney development. In mice, Six2+ nephron progenitor cells (NPCs) and …

Cellular senescence is a driver of various aging-associated disorders, including
osteoarthritis. Here, we identified a critical role for Yes-associated protein (YAP), a major …

The mechanisms underlying the role of CXCL5 in tumor angiogenesis have not been fully
defined. Here, we examined the effect of CXCL5 on tumor angiogenesis in colorectal cancer …

The mammalian kidney is a complex organ consisting of multiple cell types. We previously
showed that the Six2-expressing cap mesenchyme is a multipotent self-renewing progenitor …

Recent advances in the generation of kidney organoids and the culture of primary nephron
progenitors from mouse and human have been based on knowledge of the molecular basis …

Stem cells hold great promise in treating many diseases either through promoting
endogenous cell repair or through direct cell transplants. In order to maximize their potential …

Defining the unique molecular features of progenitors and their niche requires a genome-
wide, whole-tissue approach with cellular resolution. Here, we co-isolate embryonic hair …