Recent studies in photodynamic therapy for cancer treatment: From basic research to clinical trials

TE Kim, JE Chang - Pharmaceutics, 2023 - mdpi.com
Photodynamic therapy (PDT) is an emerging and less invasive treatment modality for
various types of cancer. This review provides an overview of recent trends in PDT research …

Novel systemic treatment modalities including immunotherapy and molecular targeted therapy for recurrent and metastatic head and neck squamous cell carcinoma

S Ghosh, PA Shah, FM Johnson - International journal of molecular …, 2022 - mdpi.com
Head and neck squamous cell carcinomas (HNSCCs) are the sixth most common cancers
worldwide. More than half of patients with HNSCC eventually experience disease …

Treg-dominant tumor microenvironment is responsible for hyperprogressive disease after PD-1 blockade therapy

H Wakiyama, T Kato, A Furusawa, R Okada… - Cancer Immunology …, 2022 - AACR
Abstract Programmed cell death 1 (PD-1) blockade therapy can result in dramatic responses
in some patients with cancer. However, about 15% of patients receiving PD-1 blockade …

Fluorescence-guided photoimmunotherapy using targeted nanotechnology and ML7710 to manage peritoneal carcinomatosis

BJ Liang, S Pang, R Perttila, CH Ma, P Srivastava… - Science …, 2023 - science.org
Fluorescence-guided intervention can bolster standard therapies by detecting and treating
microscopic tumors before lethal recurrence. Tremendous progress in photoimmunotherapy …

Review of RM-1929 Near-Infrared Photoimmunotherapy Clinical Efficacy for Unresectable and/or Recurrent Head and Neck Squamous Cell Carcinoma

NL Miyazaki, A Furusawa, PL Choyke, H Kobayashi - Cancers, 2023 - mdpi.com
Simple Summary RM-1929 near-infrared photoimmunotherapy (NIR-PIT) is an emerging
treatment that is currently being investigated under a world-wide Phase III clinical trial and …

Near-infrared photoimmunotherapy for oropharyngeal cancer

D Nishikawa, H Suzuki, S Beppu, H Terada, M Sawabe… - Cancers, 2022 - mdpi.com
Simple Summary Near-infrared photoimmunotherapy (NIR-PIT) represents a potential novel
treatment modality for a range of cancer types, including head and neck cancers. NIR-PIT is …

[HTML][HTML] Research progress in inducing immunogenic cell death of tumor cells

D Xie, Q Wang, G Wu - Frontiers in Immunology, 2022 - frontiersin.org
Immunogenic cell death (ICD) is a regulated cell death (RCD) pathway. In response to
physical and chemical signals, tumor cells activate specific signaling pathways that stimulate …

Quality-of-life evaluation of patients with unresectable locally advanced or locally recurrent head and neck carcinoma treated with head and neck …

I Okamoto, T Okada, K Tokashiki, K Tsukahara - Cancers, 2022 - mdpi.com
Simple Summary Head and neck photoimmunotherapy (HN-PIT) is a new treatment
developed for local control of head and neck carcinoma. This study assessed the quality of …

The chemical basis of cytotoxicity of silicon-phthalocyanine-based near infrared photoimmunotherapy (NIR-PIT) and its implications for treatment monitoring

H Kobayashi, PL Choyke, M Ogawa - Current Opinion in Chemical Biology, 2023 - Elsevier
Near infrared photoimmunotherapy (NIR-PIT) is a new cancer therapy based on the photo-
induced ligand release reaction of a silicon–phthalocyanine derivative, IRDye700DX …

Near-infrared photoimmunotherapy (NIR-PIT) in urologic cancers

H Fukushima, B Turkbey, PA Pinto, A Furusawa… - Cancers, 2022 - mdpi.com
Simple Summary Near-infrared photoimmunotherapy (NIR-PIT) is a novel molecularly-
targeted therapy that induces rapid cancer cell death by systemically administering an …