Alzheimer disease (AD) is the most common form of neurodegenerative disease, estimated
to contribute 60–70% of all cases of dementia worldwide. According to the prevailing …

Insulin is a peptide secreted by the pancreas and plays an important role in the regulation of
glucose metabolism in peripheral tissues. Although the role of insulin in the periphery is well …

Westernized populations are plagued by a plethora of chronic non-infectious degenerative
diseases, termed as “civilization diseases”, like obesity, diabetes, cardiovascular diseases …

Insulin plays a range of roles as an anabolic hormone in peripheral tissues. It regulates
glucose metabolism, stimulates glucose transport into cells and suppresses hepatic glucose …

Diabetic nephropathy (DN) is known as a major microvascular complication in type 1
diabetes. The effect of insulin treatment alone on controlling blood glucose is unsatisfactory …

Alzheimer's disease (AD) is defined as a severe chronic degenerative neurological disease
in human. The pathogenic mechanism of AD has been convincingly elucidated by the …

Oxidative stress and chronic inflammation are known to be associated with the development
of metabolic diseases, including diabetes. Oxidative stress, an imbalance between oxidative …

At present, the prevalence of Alzheimer's disease, a devastating neurodegenerative
disorder, is increasing. Although the mechanism of the underlying pathology is not fully …

There are different types of nutritionally mediated oxidative stress sources that trigger
inflammation. Much information indicates that high intakes of macronutrients can promote …

Numerous studies have shown that vitamin D deficiency is very common in modern societies
and is perceived as an important risk factor in the development of insulin resistance and …