Preclinical and clinical studies indicate that 3, 4-methylenedioxymethamphetamine
(MDMA;'ecstasy'), in addition to having abuse potential, may elicit acute and persistent …

Adenosine receptors (AR) are a family of G-protein coupled receptors, comprised of four
members, named A 1, A 2A, A 2B, and A 3 receptors, found widely distributed in almost all …

Background: Suicide is one of the leading causes of death worldwide and rates within the
United States have risen over the past two decades. Hence, there is a critical need for novel …

Background: Depression is a major mental health issue worldwide, with high rates of
chronicity and non-recovery associated with the condition. Existing treatments such as …

Withania somnifera (WS) is utilized in Ayurvedic medicine owing to its central and peripheral
beneficial properties. Several studies have accrued indicating that the recreational …

Clinical trials have demonstrated that 3, 4-methylenedioxymethamphetamine (MDMA)
paired with psychotherapy is more effective at reducing symptoms of post-traumatic stress …

Psychedelic and stimulating phenethylamines belong to the family of new psychoactive
substances (NPS). The acute toxicity framework has begun to be investigated, while studies …

Introduction The renewed interest in considering a range of stimulants, psychedelics and
dissociatives as therapeutics emphasizes the need to draft an updated overview of these …

Epidemiological evidence suggests a correlation between diabetes and age-related
neurodegenerative disorders, including Alzheimer's and Parkinson's diseases …

Bromo-2, 5-dimethoxy-N-(2-methoxybenzyl) phenethylamine (25B-NBOMe) is a
hallucinogen exhibiting high binding affinity for 5-HT 2A/C serotonin receptors. In the …