Multidrug efflux transporter ABCG2: expression and regulation

S Kukal, D Guin, C Rawat, S Bora, MK Mishra… - Cellular and Molecular …, 2021 - Springer
The adenosine triphosphate (ATP)-binding cassette efflux transporter G2 (ABCG2) was
originally discovered in a multidrug-resistant breast cancer cell line. Studies in the past have …

Mechanisms of resistance to chemotherapy in breast cancer and possible targets in drug delivery systems

PF Lainetti, AF Leis-Filho, R Laufer-Amorim, A Battazza… - Pharmaceutics, 2020 - mdpi.com
Breast cancer (BC) is one of the most important cancers worldwide, and usually,
chemotherapy can be used in an integrative approach. Usually, chemotherapy treatment is …

Germacrone reverses adriamycin resistance in human chronic myelogenous leukemia K562/ADM cells by suppressing MDR1 gene/P-glycoprotein expression

J Pan, D Miao, L Chen - Chemico-Biological Interactions, 2018 - Elsevier
Multidrug resistance (MDR) usually causes chemotherapy failure of chronic myelogenous
leukemia (CML). Germacrone is a terpenoid compound and has been reported to reverse …

[HTML][HTML] VASH2 promotes cell proliferation and resistance to doxorubicin in non-small cell lung cancer via AKT signaling

X Tan, Z Liao, S Zou, L Ma, A Wang - Oncology Research, 2020 - ncbi.nlm.nih.gov
Abstract Vasohibin2 (VASH2), a proangiogenic factor, has been demonstrated to play an
oncogenic role in some common human cancers. However, the detailed function of VASH2 …

Liposomal Nano-Based Drug Delivery Systems for Breast Cancer Therapy: Recent Advances and Progresses

M Yazdan, SM Naghib… - Anti-Cancer Agents in …, 2024 - ingentaconnect.com
Breast cancer is a highly prevalent disease on a global scale, with a 30% incidence rate
among women and a 14% mortality rate. Developing countries bear a disproportionate …

A preliminary study on the mechanism of VASH2 in childhood medulloblastoma

W Liu, Y Fu, M Wang, J Zhao, J Chen, Y Wang… - Scientific Reports, 2023 - nature.com
To study the differences in VASH2 expression in pediatric medulloblastoma (MB) tumor
tissues of different molecular subtypes, to analyze the correlation between VASH2 and the …

[PDF][PDF] Dezocine inhibits proliferation as well as migration of endometrial carcinoma in vitro

L Liu, B Qian, Y Li, X Zhou - European Journal of Gynaecological …, 2023 - oss.ejgo.net
Endometrial cancer (EC) includes several epithelial malignancies existed in the
endometrium tissues. To improve the prognosis of EC, it is greatly needed to find new drugs …

[PDF][PDF] VASH2 promotes oxaliplatin resistance in gastric cancer cells via the AKT signaling pathway

B Lin, Z Chen - Science Asia, 2022 - scienceasia.org
Gastric cancer (GC) is one of the most common malignant tumors worldwide. GC cells are
sensitive to chemotherapy drugs such as oxaliplatin (OHP, trans-/-diaminocyclohexane …