Recent advances in neuropeptide signaling in Drosophila, from genes to physiology and behavior

DR Nässel, M Zandawala - Progress in neurobiology, 2019 - Elsevier
This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

Insulin/IGF signaling in Drosophila and other insects: factors that regulate production, release and post-release action of the insulin-like peptides

DR Nässel, JV Broeck - Cellular and Molecular Life Sciences, 2016 - Springer
Insulin, insulin-like growth factors (IGFs) and insulin-like peptides (ILPs) are important
regulators of metabolism, growth, reproduction and lifespan, and mechanisms of insulin/IGF …

Insulin-like peptides and cross-talk with other factors in the regulation of insect metabolism

S Chowański, K Walkowiak-Nowicka, M Winkiel… - Frontiers in …, 2021 - frontiersin.org
The insulin-like peptide (ILP) and insulin-like growth factor (IGF) signalling pathways play a
crucial role in the regulation of metabolism, growth and development, fecundity, stress …

Eat to reproduce: a key role for the insulin signaling pathway in adult insects

L Badisco, P Van Wielendaele… - Frontiers in …, 2013 - frontiersin.org
Insects, like all heterotrophic organisms, acquire from their food the nutrients that are
essential for anabolic processes that lead to growth (larval stages) or reproduction (adult …

Insulin-like and IGF-like peptides in the silkmoth Bombyx mori: discovery, structure, secretion, and function

A Mizoguchi, N Okamoto - Frontiers in physiology, 2013 - frontiersin.org
A quarter of a century has passed since bombyxin, the first insulin-like peptide identified in
insects, was discovered in the silkmoth Bombyx mori. During these years, bombyxin has …

Nutrition-dependent control of insect development by insulin-like peptides

N Okamoto, N Yamanaka - Current opinion in insect science, 2015 - Elsevier
Highlights•Insulin-like peptides (ILPs) are encoded by multiple genes in insects.•Insect ILPs
are mainly produced by the brain medial neurosecretory cells (mNSCs).•Transcription and …

Dichotomous sperm in Lepidopteran insects: a biorational target for pest management

RK Seth, P Yadav, SE Reynolds - Frontiers in Insect Science, 2023 - frontiersin.org
Lepidoptera are unusual in possessing two distinct kinds of sperm, regular nucleated
(eupyrene) sperm and anucleate (apyrene) sperm ('parasperm'). Sperm of both types are …

A novel fluorescent assay for sucrose transporters

PJ Gora, A Reinders, JM Ward - Plant methods, 2012 - Springer
Background We have developed a novel assay based on the ability of type I sucrose uptake
transporters (SUTs) to transport the fluorescent coumarin β-glucoside, esculin. Budding …

Transcriptome sequencing reveals potential mechanisms of diapause preparation in bivoltine silkworm Bombyx mori (Lepidoptera: Bombycidae)

Y Chen, T Jiang, J Zhu, Y Xie, Z Tan, Y Chen… - … and Physiology Part D …, 2017 - Elsevier
In the bivoltine strain of the silkworm, Bombyx mori, embryonic diapause is induced
transgenerationally as a maternal effect. Progeny diapause ability is determined by the …

Identification of Gonadulin and Insulin-Like Growth Factor From Migratory Locusts and Their Importance in Reproduction in Locusta migratoria

JA Veenstra, J Leyria, I Orchard… - Frontiers in Endocrinology, 2021 - frontiersin.org
Many insect species have several genes coding for insulin-related peptides (IRPs), but so
far only a single IRP gene has been identified in migratory locusts. Here, we report and …