The dynamic interactions of cancer cells with their microenvironment consisting of stromal
cells (cellular part) and extracellular matrix (ECM) components (non-cellular) is essential to …

Liquid biopsy has been introduced as a new diagnostic concept predicated on the analysis
of circulating tumour cells (CTCs) or circulating tumour-derived factors, in particular, cell-free …

Simple Summary The gold standard for detecting cancer and profiling tumors is tissue
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …

Magnetic cell separation has become a key methodology for the isolation of target cell
populations from biological suspensions, covering a wide spectrum of applications from …

Understanding molecular, cellular, genetic and functional heterogeneity of tumors at the
single-cell level has become a major challenge for cancer research. The microfluidic …

Metastases and cancer recurrence are the main causes of cancer death. Circulating Tumor
Cells (CTCs) and disseminated tumor cells are the drivers of cancer cell dissemination. The …

Circulating tumor cells (CTCs) have been widely considered as promising novel biomarkers
for molecular research and clinical diagnosis of cancer. However, the sorting of CTCs is very …

Metastasis is the main cause of death in patients with cancer. The molecular mechanisms
underlying the different metastasis steps are not yet fully known, partly because most studies …

Gene mutation profiling of heterogeneous circulating tumor cells (CTCs) offers
comprehensive and real-time molecular information of tumors for targeted therapy guidance …

Analysis of circulating tumor cells (CTCs) collected from patient's blood offers a broad range
of opportunities in the field of precision oncology. With new advances in profiling technology …