[HTML][HTML] The translational potential of miR-26 in atherosclerosis and development of agents for its target genes ACC1/2, COL1A1, CPT1A, FBP1, DGAT2, and SMAD7

W Chen, X Wu, J Hu, X Liu, Z Guo, J Wu… - Cardiovascular …, 2024 - Springer
Atherosclerosis is one of the leading causes of death worldwide. miR-26 is a potential
biomarker of atherosclerosis. Standardized diagnostic tests for miR-26 (MIR26-DX) have …

A gene regulatory program controlling early Xenopus mesendoderm formation: Network conservation and motifs

RM Charney, KD Paraiso, IL Blitz, KWY Cho - Seminars in cell & …, 2017 - Elsevier
Germ layer formation is among the earliest differentiation events in metazoan embryos. In
triploblasts, three germ layers are formed, among which the endoderm gives rise to the …

[HTML][HTML] A Focal Impact Model of Traumatic Brain Injury in Xenopus Tadpoles Reveals Behavioral Alterations, Neuroinflammation, and an Astroglial Response

SL Spruiell Eldridge, JFK Teetsel, RA Torres… - International Journal of …, 2022 - mdpi.com
Traumatic Brain Injury (TBI) is a global driver of disability, and we currently lack effective
therapies to promote neural repair and recovery. TBI is characterized by an initial insult …

[HTML][HTML] P53 regulation of osteoblast differentiation is mediated through specific microRNAs

S Shah, E Pendleton, O Couture, M Broachwalla… - … and Biophysics Reports, 2021 - Elsevier
In order to understand the role of the p53 tumor suppressor gene in microRNA expression
during osteoblast differentiation, we used a screen to identify microRNAs that were altered in …

[HTML][HTML] 葛根素对成骨细胞增殖能力及靶向Runx2 的miRNA 的影响

张莹莹, 周建斌, 曾祥伟, 赵凤鸣, 刘光东, 詹秀琴 - 2016 - html.rhhz.net
目的研究葛根素作用成骨细胞MC3T3-E1 后对细胞的增殖能力和靶向Runx2 基因的miRNA
的影响. 方法① MTT 法检测葛根素作用于MC3T3-E1 细胞后对成骨细胞增殖能力的影响. ② …

MicroRNA26a Overexpression Hastens Osteoblast Differentiation Capacity in Dental Stem Cells

S Kaufman, P Chang, E Pendleton… - Cellular …, 2023 - liebertpub.com
Dental pulp stem cells (DPSCs) and stem cells from human exfoliated deciduous teeth
(SHED) are a source of mesenchymal stem cells with the potential to differentiate into …

[HTML][HTML] MicroRNAs and ectodermal specification I. Identification of miRs and miR-targeted mRNAs in early anterior neural and epidermal ectoderm

VV Shah, B Soibam, RA Ritter, A Benham… - Developmental …, 2017 - Elsevier
The establishment of cell lineages occurs via a dynamic progression of gene regulatory
networks (GRNs) that underlie developmental commitment and differentiation. To investigate …

miR‐199 plays both positive and negative regulatory roles in Xenopus eye development

RA Ritter, CH Ulrich, BN Brzezinska, VV Shah… - genesis, 2020 - Wiley Online Library
To investigate microRNA (miR) functions in early eye development, we asked whether eye
field transcription factors (EFTFs) are targets of miR‐dependent regulation in Xenopus …

[HTML][HTML] Data on microRNAs and microRNA-targeted mRNAs in Xenopus ectoderm

VV Shah, B Soibam, RA Ritter, A Benham, J Oomen… - Data in brief, 2016 - Elsevier
Small RNAs from early neural (ie, Noggin-expressing, or NOG) and epidermal (expressing a
constitutively active BMP4 receptor, CABR) ectoderm in Xenopus laevis were sequenced to …

A role for Shh and Bmp4 in regulating the dorsal-ventral patterning of the developing pharyngeal region

A Szpak - 2019 - search.proquest.com
The pharynx is crucial to the survival of all vertebrates since it facilitates respiration by
connecting the nasal and oral cavity to the larynx and digestion by connecting the oral cavity …