Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

Functionalizing nanoparticles with biological molecules: developing chemistries that facilitate nanotechnology

KE Sapsford, WR Algar, L Berti, KB Gemmill… - Chemical …, 2013 - ACS Publications
Bionanotechnology has now become firmly established in its own right as one of the
principle and focused subdisciplines within nanotechnology.(1-10) Bionanotechnology can …

Multifunctional gold nanoparticles for diagnosis and therapy of disease

AJ Mieszawska, WJM Mulder, ZA Fayad… - Molecular …, 2013 - ACS Publications
Gold nanoparticles (AuNPs) have a number of physical properties that make them appealing
for medical applications. For example, the attenuation of X-rays by gold nanoparticles has …

Revisiting 30 years of biofunctionalization and surface chemistry of inorganic nanoparticles for nanomedicine

J Conde, JT Dias, V Grazú, M Moros… - Frontiers in …, 2014 - frontiersin.org
In the last 30 years we have assisted to a massive advance of nanomaterials in material
science. Nanomaterials and structures, in addition to their small size, have properties that …

Nanostructured materials-based nanosensors

R Abdel-Karim, Y Reda… - Journal of The …, 2020 - iopscience.iop.org
Nanosensors are sensing devices with at least one of their sensing dimensions being up
to100 nm. In the field of nanotechnology, nanosensors are instrumental for (a) detecting …

Nanotechnology-Enhanced No-Wash Biosensors for in Vitro Diagnostics of Cancer

X Huang, Y Liu, B Yung, Y Xiong, X Chen - ACS nano, 2017 - ACS Publications
In vitro biosensors have been an integral component for early diagnosis of cancer in the
clinic. Among them, no-wash biosensors, which only depend on the simple mixing of the …

The controlled display of biomolecules on nanoparticles: a challenge suited to bioorthogonal chemistry

WR Algar, DE Prasuhn, MH Stewart… - Bioconjugate …, 2011 - ACS Publications
Interest in developing diverse nanoparticle (NP)-biological composite materials continues to
grow almost unabated. This is motivated primarily by the desire to simultaneously exploit the …

Designing the nanoparticle–biomolecule interface for “targeting and therapeutic delivery”

E Mahon, A Salvati, FB Bombelli, I Lynch… - Journal of Controlled …, 2012 - Elsevier
The endogenous transport mechanisms which occur in living organisms have evolved to
allow selective transport and processing operate on a scale of tens of nanometers. This …

Chemical sensors that incorporate click-derived triazoles

YH Lau, PJ Rutledge, M Watkinson… - Chemical Society …, 2011 - pubs.rsc.org
Since the advent of click chemistry in 2001, the 1, 4-disubstituted triazole has become an
increasingly common motif in chemical sensors. Although these click-derived triazoles are …

Strategies for in vivo imaging of enzyme activity: an overview and recent advances

A Razgulin, N Ma, J Rao - Chemical Society reviews, 2011 - pubs.rsc.org
Imaging of enzyme activity in living subjects promises many applications in both basic and
translational researches from helping elucidate the enzyme function and mechanism in …