Biological utility of fluorinated compounds: from materials design to molecular imaging, therapeutics and environmental remediation

C Zhang, K Yan, C Fu, H Peng, CJ Hawker… - Chemical …, 2021 - ACS Publications
The applications of fluorinated molecules in bioengineering and nanotechnology are
expanding rapidly with the controlled introduction of fluorine being broadly studied due to …

Towards more accurate bioimaging of drug nanocarriers: turning aggregation-caused quenching into a useful tool

J Qi, X Hu, X Dong, Y Lu, H Lu, W Zhao… - Advanced Drug Delivery …, 2019 - Elsevier
One of the current challenges in the monitoring of drug nanocarriers lies in the difficulties in
discriminating the carrier-bound signals from the bulk signals of probes. Environment …

[HTML][HTML] Toxicity of manufactured nanomaterials

Y Liu, S Zhu, Z Gu, C Chen, Y Zhao - Particuology, 2022 - Elsevier
Manufactured nanomaterials with unique properties have been extensively applied in
various industrial, agricultural or medical fields. However, some of the properties have been …

Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification

Q Shi, H Yin, R Song, J Xu, J Tan, X Zhou, J Cen… - Nature Chemistry, 2023 - nature.com
Identification and quantification of synthetic polymers in complex biological milieu are crucial
for delivery, sensing and scaffolding functions, but conventional techniques based on …

DNAzyme-powered three-dimensional DNA walker nanoprobe for detection amyloid β-peptide oligomer in living cells and in vivo

Y Yin, G Chen, L Gong, K Ge, W Pan, N Li… - Analytical …, 2020 - ACS Publications
Amyloid β-peptide oligomer (AβO) is widely acknowledged as the promising biomarker for
the diagnosis of Alzheimer's disease (AD). In this work, we designed a three-dimensional …

Absorption, distribution, metabolism, and excretion of nanocarriers in vivo and their influences

A Zhang, K Meng, Y Liu, Y Pan, W Qu, D Chen… - Advances in colloid and …, 2020 - Elsevier
As one of the most promising and effective delivery systems for targeted controlled-release
drugs, nanocarriers (NCs) have been widely studied. Although the development of …

Super Wide-Field Photoacoustic Microscopy of Animals and Humans In Vivo

JW Baik, JY Kim, S Cho, S Choi… - IEEE transactions on …, 2019 - ieeexplore.ieee.org
Acoustic-resolution photoacoustic micro-scopy (AR-PAM) is an emerging biomedical
imaging modality that combines superior optical sensitivity and fine ultrasonic resolution in …

Stromal modulation and treatment of metastatic pancreatic cancer with local intraperitoneal triple miRNA/siRNA nanotherapy

Y Xie, Y Hang, Y Wang, R Sleightholm, DR Prajapati… - ACS …, 2020 - ACS Publications
Nanomedicines achieve tumor-targeted delivery mainly through enhanced permeability and
retention (EPR) effect following intravenous (IV) administration. Unfortunately, the EPR effect …

[HTML][HTML] Bioinspired tumor-homing nanoplatform for co-delivery of paclitaxel and siRNA-E7 to HPV-related cervical malignancies for synergistic therapy

C Xu, W Liu, Y Hu, W Li, W Di - Theranostics, 2020 - ncbi.nlm.nih.gov
Because of the complexity of cancer, a combination of chemotherapy and gene therapy is an
emerging treatment modality. To realize the full potential of this strategy, a smart, highly …

Current limitations and recent progress in nanomedicine for clinically available photodynamic therapy

J Park, YK Lee, IK Park, SR Hwang - Biomedicines, 2021 - mdpi.com
Photodynamic therapy (PDT) using oxygen, light, and photosensitizers has been receiving
great attention, because it has potential for making up for the weakness of the existing …