Background Anxiety and depression are common psychological comorbidities that impact
the quality of life (QoL) of patients. In this systematic review, we 1) determined the impact of …

Osteoarthritis is a disease that progresses over time and culminates in the destruction of
articular cartilage and joints. Thus, with an increasing elderly population the treatment of …

The pathogenesis of osteoarthritis (OA) is poorly understood, and therapeutic approaches
are limited to preventing progression of the disease. Recent studies have shown that …

Objectives Osteoarthritis (OA) is a leading cause of disability, but the relationship with
premature mortality remains uncertain. We aimed to investigate the relationship between OA …

Background Exercise or physical activity is recommended for improving pain and functional
status in people with knee or hip osteoarthritis. These are complex interventions whose …

Abstract Background in October 2018, the European Working Group on Sarcopenia in Older
People 2 (EWGSOP2) updated their original definition of sarcopenia to reflect the scientific …

Background This study aimed to quantify the absenteeism costs of knee and hip
osteoarthritis in the Netherlands for the Dutch workforce and specific groups of workers …

Despite acknowledgement in the scientific community of sex-based differences in cartilage
biology, the implications for study design remain unclear, with many studies continuing to …

Background Currently, there is poor evidence of the effect of hydrotherapy alone on patients
with hip or knee osteoarthritis. Objectives The study aimed to assess the impact of …

Estrogen deficiency has been regarded as the main causative factor in menopausal
symptoms and diseases. Here, we show that although estrogen decreases by 90%, a …