[HTML][HTML] Addressing the global snakebite crisis with geo-spatial analyses–Recent advances and future direction

AFV Pintor, N Ray, J Longbottom, CA Bravo-Vega… - Toxicon: X, 2021 - Elsevier
Venomous snakebite is a neglected tropical disease that annually leads to hundreds of
thousands of deaths or long-term physical and mental ailments across the developing world …

Evolutionary ecology of fish venom: adaptations and consequences of evolving a venom system

RJ Harris, RA Jenner - Toxins, 2019 - mdpi.com
Research on venomous animals has mainly focused on the molecular, biochemical, and
pharmacological aspects of venom toxins. However, it is the relatively neglected broader …

When one phenotype is not enough: divergent evolutionary trajectories govern venom variation in a widespread rattlesnake species

G Zancolli, JJ Calvete, MD Cardwell… - … of the Royal …, 2019 - royalsocietypublishing.org
Understanding the origin and maintenance of phenotypic variation, particularly across a
continuous spatial distribution, represents a key challenge in evolutionary biology. For this …

The Tiger Rattlesnake genome reveals a complex genotype underlying a simple venom phenotype

MJ Margres, RM Rautsaw… - Proceedings of the …, 2021 - National Acad Sciences
Variation in gene regulation is ubiquitous, yet identifying the mechanisms producing such
variation, especially for complex traits, is challenging. Snake venoms provide a model …

The roles of balancing selection and recombination in the evolution of rattlesnake venom

DR Schield, BW Perry, RH Adams, ML Holding… - Nature ecology & …, 2022 - nature.com
The origin of snake venom involved duplication and recruitment of non-venom genes into
venom systems. Several studies have predicted that directional positive selection has …

Snakes on a plain: biotic and abiotic factors determine venom compositional variation in a wide-ranging generalist rattlesnake

CF Smith, ZL Nikolakis, K Ivey, BW Perry, DR Schield… - BMC biology, 2023 - Springer
Background Snake venoms are trophic adaptations that represent an ideal model to
examine the evolutionary factors that shape polymorphic traits under strong natural …

[HTML][HTML] Mutual enlightenment: A toolbox of concepts and methods for integrating evolutionary and clinical toxinology via snake venomics and the contextual stance

JJ Calvete, B Lomonte, AJ Saviola, F Bonilla, M Sasa… - Toxicon: X, 2021 - Elsevier
Snakebite envenoming is a neglected tropical disease that may claim over 100,000 human
lives annually worldwide. Snakebite occurs as the result of an interaction between a human …

Allopatric divergence and secondary contact with gene flow: a recurring theme in rattlesnake speciation

DR Schield, BW Perry, RH Adams… - Biological Journal of …, 2019 - academic.oup.com
The study of recently diverged lineages whose geographical ranges come into contact can
provide insight into the early stages of speciation and the potential roles of reproductive …

One Size Fits All—Venomics of the Iberian Adder (Vipera seoanei, Lataste 1878) Reveals Low Levels of Venom Variation across Its Distributional Range

I Avella, M Damm, I Freitas, W Wüster, N Lucchini… - Toxins, 2023 - mdpi.com
European vipers (genus Vipera) are medically important snakes displaying considerable
venom variation, occurring at different levels in this group. The presence of intraspecific …

[HTML][HTML] Comparative characterization of Viperidae snake venoms from Perú reveals two compositional patterns of phospholipase A2 expression

B Lomonte, C Díaz, F Chaves, J Fernández, M Ruiz… - Toxicon: X, 2020 - Elsevier
Snake species within the Bothrops complex (sensu lato) are of medical relevance in Latin
America, but knowledge on their venom characteristics is limited, or even unavailable, for …