Metabolic engineering and synthetic biology strategies for producing high-value natural pigments in Microalgae
K Cao, Y Cui, F Sun, H Zhang, J Fan, B Ge, Y Cao… - Biotechnology …, 2023 - Elsevier
Microalgae are microorganisms capable of producing bioactive compounds using
photosynthesis. Microalgae contain a variety of high value-added natural pigments such as …
photosynthesis. Microalgae contain a variety of high value-added natural pigments such as …
Challenges and advances towards the rational design of microalgal synthetic promoters in Chlamydomonas reinhardtii
Microalgae hold enormous potential to provide a safe and sustainable source of high-value
compounds, acting as carbon-fixing biofactories that could help to mitigate rapidly …
compounds, acting as carbon-fixing biofactories that could help to mitigate rapidly …
Harnessing genetic engineering to drive economic bioproduct production in algae
Our reliance on agriculture for sustenance, healthcare, and resources has been essential
since the dawn of civilization. However, traditional agricultural practices are no longer …
since the dawn of civilization. However, traditional agricultural practices are no longer …
Optimized production of a bioactive human recombinant protein from the microalgae Chlamydomonas reinhardtii grown at high density in a fed-batch bioreactor
Microalgae have been identified as an alternative platform to produce high-quality biomass
and subsequent bioproducts, such as foods, feeds, nutritional supplements, recombinant …
and subsequent bioproducts, such as foods, feeds, nutritional supplements, recombinant …
Immunomodulatory compounds from the sea: From the origins to a modern marine pharmacopoeia
From sea shores to the abysses of the deep ocean, marine ecosystems have provided
humanity with valuable medicinal resources. The use of marine organisms is discussed in …
humanity with valuable medicinal resources. The use of marine organisms is discussed in …
The Clinical Promise of Microalgae in Rheumatoid Arthritis: From Natural Compounds to Recombinant Therapeutics
Rheumatoid arthritis (RA) is an invalidating chronic autoimmune disorder characterized by
joint inflammation and progressive bone damage. Dietary intervention is an important …
joint inflammation and progressive bone damage. Dietary intervention is an important …
Harnessing light‐harvesting chlorophyll a/b‐binding proteins for multiple abiotic stress tolerance in Chlamydomonas reinhardtii: Insights from genomic and …
Light‐harvesting chlorophyll a/b‐binding proteins (LHC) of photosystem II perform key
functions in various processes, eg, photosynthesis, development, and abiotic stress …
functions in various processes, eg, photosynthesis, development, and abiotic stress …
Characterization of activating cis‐regulatory elements from the histone genes of Chlamydomonas reinhardtii
Y Lihanova, R Nagel, T Jakob, S Sasso - The Plant Journal, 2024 - Wiley Online Library
Regulation of gene expression in eukaryotes is controlled by cis‐regulatory modules
(CRMs). A major class of CRMs are enhancers which are composed of activating cis …
(CRMs). A major class of CRMs are enhancers which are composed of activating cis …
Proteomic analysis reveals molecular changes following genetic engineering in Chlamydomonas reinhardtii
Chlamydomonas reinhardtii is gaining recognition as a promising expression system for the
production of recombinant proteins. However, its performance as a cellular biofactory …
production of recombinant proteins. However, its performance as a cellular biofactory …
[HTML][HTML] Design and synthesis of synthetic promoters for consistency of gene expression across growth phases and scale in S. cerevisiae
KV Presnell, O Melhem, SM Coleman, NJ Morse… - Synthetic and Systems …, 2024 - Elsevier
Metabolic engineering and synthetic biology endeavors benefit from promoters that perform
consistently (or robustly) with respect to cellular growth phase (exponential and stationary) …
consistently (or robustly) with respect to cellular growth phase (exponential and stationary) …