Myelin is critical for healthy brain function. An accurate in vivo measure of myelin content
has important implications for understanding brain plasticity and neurodegenerative …

Multiexponential T2 relaxation time measurement in the central nervous system shows a
component that originates from water trapped between the lipid bilayers of myelin. This …

Recent studies have shown that there is a direct link between the orientation of the nerve
fibers in white matter (WM) and the contrast observed in magnitude and phase images …

Here, we describe a quantitative neuroimaging method to estimate the macromolecular
tissue volume (MTV), a fundamental measure of brain anatomy. By making measurements …

Myelin water imaging, a magnetic resonance imaging technique capable of resolving the
fraction of water molecules which are located between the layers of myelin, is a valuable tool …

Various magnetic resonance (MR) techniques are used to study the pathological evolution
of demyelinating diseases, such as multiple sclerosis (MS). However, few studies have …

Myelin water imaging (MWI) promises to be invaluable in understanding neurological
diseases like MS. However, a limitation of MWI is signal to noise ratio. Recently, a number of …

Conventional MR images are qualitative, and their signal intensity is dependent on several
complementary contrast mechanisms that are manipulated by the MR hardware and …

The ability to measure myelin in vivo has great consequences for furthering our knowledge
of normal development, as well as for understanding a wide range of neurological disorders …

Hydrogen 1 (1H) magnetic resonance (MR) spectroscopy enables noninvasive in vivo
quantification of metabolite concentrations in the brain. Currently, metabolite concentrations …