Platelets have traditionally been viewed as fragmentary mediators of coagulation. However,
recent molecular and cellular evidence suggests that they have multiple roles in host …

Blood platelets are here presented as active players in antimicrobial host defense and the
induction of inflammation and tissue repair in addition to their participation in hemostasis …

Platelets share structural and functional similarities with granulocytes known to participate in
antimicrobial host defense. To evaluate the potential antimicrobial activities of platelet …

Platelets interact with bacterial pathogens through a wide array of cellular and molecular
mechanisms. The consequences of this interaction may significantly influence the balance …

Platelets are the main players in thrombosis and hemostasis; however they also play
important roles during inflammation and infection. Through their surface receptors, platelets …

Platelets exhibit archetypal structures and functions enabling their roles as multifunctional
host defense cells. Beyond roles in hemostasis and wound repair, platelets sense and …

Antibacterial proteins are components of the innate immune system found in many
organisms and produced by a variety of cell types. Human blood platelets contain a number …

Infective endocarditis is a life‐threatening and enigmatic disease with a mortality of 30% and
a pathophysiology that is poorly understood. However, at its core, an endocarditis lesion is …

Background Percutaneous endoscopic gastrostomy (PEG) is a relatively safe procedure;
however, acute and chronic complications of PEG have been reported. We aimed to …

The coagulation system does not only offer protection against bleeding, but also aids in our
defense against invading microorganisms. The hemostatic system and innate immunity are …