Exosome processing and characterization approaches for research and technology development

JJ Lai, ZL Chau, SY Chen, JJ Hill… - Advanced …, 2022 - Wiley Online Library
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …

[HTML][HTML] Extracellular vesicles: a rising star for therapeutics and drug delivery

S Du, Y Guan, A Xie, Z Yan, S Gao, W Li, L Rao… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …

[HTML][HTML] Isolation and characterization of exosomes for cancer research

L Zhu, HT Sun, S Wang, SL Huang, Y Zheng… - Journal of hematology & …, 2020 - Springer
Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins,
nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes …

Bone‐targeted exosomes: strategies and applications

J Wang, X Li, S Wang, J Cui, X Ren… - Advanced healthcare …, 2023 - Wiley Online Library
As the global population ages, bone‐related diseases have increasingly become a major
social problem threatening human health. Exosomes, as natural cell products, have been …

Copper‐free click chemistry: applications in drug delivery, cell Tracking, and tissue engineering

HY Yoon, D Lee, DK Lim, H Koo, K Kim - Advanced Materials, 2022 - Wiley Online Library
Traditionally, organic chemical reactions require organic solvents, toxic catalysts, heat, or
high pressure. However, copper‐free click chemistry has been shown to have favorable …

Application of “click” chemistry in biomedical hydrogels

X Li, Y Xiong - ACS omega, 2022 - ACS Publications
Since “click” chemistry was first reported in 2001, it has remained a popular research topic in
the field of chemistry due to its high yield without byproducts, fast reaction rate, simple …

[HTML][HTML] Camouflage strategies for therapeutic exosomes evasion from phagocytosis

N Parada, A Romero-Trujillo, N Georges… - Journal of advanced …, 2021 - Elsevier
Background Even though exosome-based therapy has been shown to be able to control the
progression of different pathologies, the data revealed by pharmacokinetic studies warn of …

[HTML][HTML] Small extracellular vesicles in cancer

K Abhange, A Makler, Y Wen, N Ramnauth, W Mao… - Bioactive Materials, 2021 - Elsevier
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …

Resveratrol-loaded macrophage exosomes alleviate multiple sclerosis through targeting microglia

X Zheng, K Sun, Y Liu, X Yin, H Zhu, F Yu… - Journal of Controlled …, 2023 - Elsevier
Despite exosome promise as endogenous drug delivery vehicles, the current understanding
of exosome may be insufficient to develop their various applications. Here we synthesized …

[HTML][HTML] Organically derived exosomes as carriers of anticancer drugs and imaging agents for cancer treatment

A Srivastava, S Rathore, A Munshi… - Seminars in cancer biology, 2022 - Elsevier
Extracellular vesicles (EVs), is the umbrella term used for different types of vesicles
produced by the cells, among which exosomes form the largest group. Exosomes perform …