Nuclear ribonuclease (RNase) P is a ubiquitous essential ribonucleoprotein complex, one of
only two known RNA-based enzymes found in all three domains of life. The RNA component …

Structural proteomics approaches using mass spectrometry are increasingly used in biology
to examine the composition and structure of macromolecules. Hydroxyl radical–mediated …

Ribonuclease (RNase) P is the universal ribozyme responsible for 5′-end tRNA
processing. We report the crystal structure of the Thermotoga maritima RNase P …

Abstract Ribonuclease P (RNase P) is a ubiquitous endonuclease that catalyses the
maturation of the 5′ end of transfer RNA (tRNA). Although it carries out a biochemically …

Transfer RNA (tRNA) is produced as a precursor molecule that needs to be processed at its
3′ and 5′ ends. Ribonuclease P is the sole endonuclease responsible for processing the …

The field of RNA structure prediction has experienced significant advances in the past
several years, thanks to the availability of new experimental data and improved …

Transfer‐RNA (tRNA) molecules are essential players in protein biosynthesis. They are
transcribed as precursors, which have to be extensively processed at both ends to become …

Many non-coding RNAs form structures that interact with cellular machinery to control gene
expression. A central goal of molecular and synthetic biology is to uncover design principles …

Ferritins are known as important iron storage/detoxification proteins and are widely found in
living organisms. This report details the 2.1 Å resolution native and 2.7 Å resolution iron …

Understanding the molecular mechanism of protein–RNA recognition and complex
formation is a major challenge in structural biology. Unfortunately, the experimental …