Ferroptosis as a mechanism of non-ferrous metal toxicity

M Aschner, AV Skalny, AC Martins, AI Sinitskii… - Archives of …, 2022 - Springer
Ferroptosis is a recently discovered form of regulated cell death, implicated in multiple
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …

Redox interactions and genotoxicity of metal-based nanoparticles: A comprehensive review

K Mortezaee, M Najafi, H Samadian, H Barabadi… - Chemico-biological …, 2019 - Elsevier
Nanotechnology is a growing science that may provide several new applications for
medicine, food preservation, diagnostic technologies, and sanitation. Despite its beneficial …

Clustered cobalt nanodots initiate ferroptosis by upregulating heme oxygenase 1 for radiotherapy sensitization

J Zhao, Y Chen, T Xiong, S Han, C Li, Y He, Y He… - Small, 2023 - Wiley Online Library
High cobalt (Co) levels in tumors are associated with good clinical prognosis. An anticancer
regimen that increases intratumoral Co through targeted nanomaterial delivery is proposed …

Effects of acute ammonia toxicity on oxidative stress, DNA damage and apoptosis in digestive gland and gill of Asian clam (Corbicula fluminea)

T Zhang, Z Yan, X Zheng, S Wang, J Fan… - Fish & Shellfish …, 2020 - Elsevier
Ammonia is one of the major pollutants associated with the main river basins due to
ammonification of uneaten food and animal excretion, which usually brings detrimental …

Genotoxicity of metal oxide nanomaterials: review of recent data and discussion of possible mechanisms

N Golbamaki, B Rasulev, A Cassano, RLM Robinson… - Nanoscale, 2015 - pubs.rsc.org
Nanotechnology has rapidly entered into human society, revolutionized many areas,
including technology, medicine and cosmetics. This progress is due to the many valuable …

Cobalt: its role in health and disease

K Yamada - Interrelations between essential metal ions and human …, 2013 - Springer
The primarily function of cobalt in humans is based on its role in cobalamin (Cbl, vitamin B
12). Therefore, this chapter will focus on the physiological roles of Cbl and the importance of …

Systemic and local toxicity of metal debris released from hip prostheses: A review of experimental approaches

DR Bijukumar, A Segu, JCM Souza, XJ Li… - … , Biology and Medicine, 2018 - Elsevier
Despite the technological improvements in orthopedic joint replacement implants, wear and
corrosion products associated with the metal components of these implants may result in …

Biosynthesis of cobalt oxide nanoparticles (Co3O4-NPs) using Caccinia macranthera extract and evaluation of their cytotoxicity and photocatalytic activity

A Mohandes, MR Aghamaali, Z Sabouri… - Materials Science and …, 2023 - Elsevier
A novel green synthesis of cobalt oxide nanoparticles (Co 3 O 4-NPs) has been conducted
using Caccinia macranthera seed extract as a renewable and non-toxic reducing agent. The …

Induction of apoptosis and antiproliferative activity of naringenin in human epidermoid carcinoma cell through ROS generation and cell cycle arrest

MS Ahamad, S Siddiqui, A Jafri, S Ahmad, M Afzal… - PloS one, 2014 - journals.plos.org
A natural predominant flavanone naringenin, especially abundant in citrus fruits, has a wide
range of pharmacological activities. The search for antiproliferative agents that reduce skin …

Comparative cytotoxicity and genotoxicity of cobalt (II, III) oxide, iron (III) oxide, silicon dioxide, and aluminum oxide nanoparticles on human lymphocytes in vitro

S Rajiv, J Jerobin, V Saranya… - Human & …, 2016 - journals.sagepub.com
Despite the extensive use of nanoparticles (NPs) in various fields, adequate knowledge of
human health risk and potential toxicity is still lacking. The human lymphocytes play a major …