In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

Stroke remains a leading cause of death and disability in the world. Over the past few
decades our understanding of the pathophysiology of stroke has increased, but greater …

Stem cell-based approaches to restore function after stroke through replacement of dead
neurons require the generation of specific neuronal subtypes. Loss of neurons in the …

Cerebral ischemia is one of the leading causes of morbidity and mortality worldwide.
Although stroke (a form of cerebral ischemia)-related costs are expected to reach 240.67 …

Transplanted neurons derived from stem cells have been proposed to improve function in
animal models of human disease by various mechanisms such as neuronal replacement …

Stroke is a leading cause of adult disability. Stem/progenitor cell transplantation improves
recovery after stroke in rodent models. These studies have 2 main limitations to clinical …

Stroke is the leading cause of adult disability with≈ 80% being ischemic. Stem cell
transplantation has been shown to improve functional recovery. However, the overall …

Background and Purpose—Hypoxic–ischemic (HI) brain injury in newborn infants
represents a major cause of cerebral palsy, development delay, and epilepsy. Stem cell …

Recent advancements in stem cell biology and neuromodulation have ushered in a battery
of new neurorestorative therapies for ischemic stroke. While the understanding of stroke …