Platinum-based drugs cisplatin, carboplatin, and oxaliplatin are widely used for
chemotherapeutic eradication of cancer. However, the side effects of platinum drugs, such …

Metal-based compounds form a promising class of therapeutic agents, whose mechanisms
of action still need to be elucidated, and that are in general prone to undergo extensive …

Improving efficacy and lowering resistance to metal-based drugs can be addressed by
consideration of the coordination complex speciation and key reactions important to …

Mass spectrometry has been widely utilised in the study of nucleobases, nucleosides and
nucleotides as components of nucleic acids and as bioactive metabolites in their own right …

DNA adducting drugs, including alkylating agents and platinum-containing drugs, are
prominent in cancer chemotherapy. Their mechanisms of action involve direct interaction …

Metallomics is a relatively new branch of omics with a growing interest. The study of
metallomes is becoming more focused in certain metabolites and the screening of various …

Method development and applications of hyphenated techniques as tools for speciation
analysis of metal-based pharmaceuticals are summarized within this review. Advantages …

Three reversed-phase liquid chromatography (RPLC) stationary phases were obtained by
using long-chain 1-octadecene (OD) co-grafted with three short-chain monomers, including …

We synthesized and characterized bioactive metal (II) complexes from a pyrimidine‐based
Schiff base ligand, 4‐[2‐(4‐chlorobenzylidene) hydrazinyl]‐7H‐pyrrolo [2, 3‐d] pyrimidine …

This work offers an overview of the platinum (II, IV) complexes involving adenine or its
derivatives coordinated to platinum through N-or C-donor atom (s) of the adenine moiety …