Techniques for determining contact angle and wettability of powders

A Alghunaim, S Kirdponpattara, BZ Newby - Powder Technology, 2016 - Elsevier
This review summarizes some common methods for determining the wettability of powders,
especially the contact angle that a liquid would form on powders. The sessile drop, Wilhelmy …

Manufacturing of solid dispersions of poorly water soluble drugs by spray drying: formulation and process considerations

A Paudel, ZA Worku, J Meeus, S Guns… - International journal of …, 2013 - Elsevier
Spray drying is an efficient technology for solid dispersion manufacturing since it allows
extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to …

Stability of nanosuspensions in drug delivery

Y Wang, Y Zheng, L Zhang, Q Wang… - Journal of controlled …, 2013 - Elsevier
Nanosuspensions are nanosized colloidal dispersion systems that are stabilized by
surfactants and/or polymers. Because nanosizing results in the creation of new interfaces …

Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs

CAS Bergström, R Holm, SA Jørgensen… - European Journal of …, 2014 - Elsevier
Preformulation measurements are used to estimate the fraction absorbed in vivo for orally
administered compounds and thereby allow an early evaluation of the need for enabling …

[HTML][HTML] Binder jetting 3D printing of challenging medicines: from low dose tablets to hydrophobic molecules

M Kozakiewicz-Latała, KP Nartowski, A Dominik… - European Journal of …, 2022 - Elsevier
Increasing access to additive manufacturing technologies utilising easily available desktop
devices opened novel ways for formulation of personalized medicines. It is, however …

[HTML][HTML] Parenteral nanosuspensions: a brief review from solubility enhancement to more novel and specific applications

E Ahire, S Thakkar, M Darshanwad, M Misra - Acta pharmaceutica sinica B, 2018 - Elsevier
Advancements in in silico techniques of lead molecule selection have resulted in the failure
of around 70% of new chemical entities (NCEs). Some of these molecules are getting …

Influence of surface roughness on the dynamics and crystallization of vapor-deposited thin films

A Beena Unni, R Winkler, DM Duarte… - The Journal of …, 2022 - ACS Publications
The substrate roughness is a very important parameter that can influence the properties of
supported thin films. In this work, we investigate the effect of surface roughness on the …

Water-in-oil Pickering emulsions stabilized solely by water-dispersible phytosterol particles

M Lan, Y Song, S Ou, J Zheng, C Huang, Y Wang… - Langmuir, 2020 - ACS Publications
Water-in-oil (W/O) Pickering emulsions were successfully synthesized by water-dispersible
phytosterol (PS) particles formed through simple antisolvent precipitation. The effects of the …

[HTML][HTML] The biomolecular gastrointestinal corona in oral drug delivery

A Aljabbari, S Kihara, T Rades, BJ Boyd - Journal of Controlled Release, 2023 - Elsevier
The formation of a biomolecular corona on exogenous particles in plasma is well studied
and is known to dictate the biodistribution and cellular interactions of nanomedicine …

Dynamic vapor sorption as a tool for characterization and quantification of amorphous content in predominantly crystalline materials

S Sheokand, SR Modi, AK Bansal - Journal of pharmaceutical sciences, 2014 - Elsevier
It is well established that pharmaceutical processing can cause disruption of the crystal
structure, leading to generation of amorphous content in crystalline materials. The presence …