Techniques for determining contact angle and wettability of powders
This review summarizes some common methods for determining the wettability of powders,
especially the contact angle that a liquid would form on powders. The sessile drop, Wilhelmy …
especially the contact angle that a liquid would form on powders. The sessile drop, Wilhelmy …
Manufacturing of solid dispersions of poorly water soluble drugs by spray drying: formulation and process considerations
Spray drying is an efficient technology for solid dispersion manufacturing since it allows
extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to …
extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to …
Stability of nanosuspensions in drug delivery
Y Wang, Y Zheng, L Zhang, Q Wang… - Journal of controlled …, 2013 - Elsevier
Nanosuspensions are nanosized colloidal dispersion systems that are stabilized by
surfactants and/or polymers. Because nanosizing results in the creation of new interfaces …
surfactants and/or polymers. Because nanosizing results in the creation of new interfaces …
Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs
CAS Bergström, R Holm, SA Jørgensen… - European Journal of …, 2014 - Elsevier
Preformulation measurements are used to estimate the fraction absorbed in vivo for orally
administered compounds and thereby allow an early evaluation of the need for enabling …
administered compounds and thereby allow an early evaluation of the need for enabling …
[HTML][HTML] Binder jetting 3D printing of challenging medicines: from low dose tablets to hydrophobic molecules
M Kozakiewicz-Latała, KP Nartowski, A Dominik… - European Journal of …, 2022 - Elsevier
Increasing access to additive manufacturing technologies utilising easily available desktop
devices opened novel ways for formulation of personalized medicines. It is, however …
devices opened novel ways for formulation of personalized medicines. It is, however …
[HTML][HTML] Parenteral nanosuspensions: a brief review from solubility enhancement to more novel and specific applications
Advancements in in silico techniques of lead molecule selection have resulted in the failure
of around 70% of new chemical entities (NCEs). Some of these molecules are getting …
of around 70% of new chemical entities (NCEs). Some of these molecules are getting …
Influence of surface roughness on the dynamics and crystallization of vapor-deposited thin films
A Beena Unni, R Winkler, DM Duarte… - The Journal of …, 2022 - ACS Publications
The substrate roughness is a very important parameter that can influence the properties of
supported thin films. In this work, we investigate the effect of surface roughness on the …
supported thin films. In this work, we investigate the effect of surface roughness on the …
Water-in-oil Pickering emulsions stabilized solely by water-dispersible phytosterol particles
M Lan, Y Song, S Ou, J Zheng, C Huang, Y Wang… - Langmuir, 2020 - ACS Publications
Water-in-oil (W/O) Pickering emulsions were successfully synthesized by water-dispersible
phytosterol (PS) particles formed through simple antisolvent precipitation. The effects of the …
phytosterol (PS) particles formed through simple antisolvent precipitation. The effects of the …
[HTML][HTML] The biomolecular gastrointestinal corona in oral drug delivery
The formation of a biomolecular corona on exogenous particles in plasma is well studied
and is known to dictate the biodistribution and cellular interactions of nanomedicine …
and is known to dictate the biodistribution and cellular interactions of nanomedicine …
Dynamic vapor sorption as a tool for characterization and quantification of amorphous content in predominantly crystalline materials
It is well established that pharmaceutical processing can cause disruption of the crystal
structure, leading to generation of amorphous content in crystalline materials. The presence …
structure, leading to generation of amorphous content in crystalline materials. The presence …