Substances of interest that support glaucoma therapy

SC Saccà, P Corazza, S Gandolfi, D Ferrari, S Sukkar… - Nutrients, 2019 - mdpi.com
Glaucoma is a multifactorial disease in which pro-apoptotic signals are directed to retinal
ganglion cells. During this disease the conventional outflow pathway becomes …

Novel classification of early-stage systemic hypertensive changes in human retina based on OCTA measurement of choriocapillaris

K Takayama, H Kaneko, Y Ito, K Kataoka, T Iwase… - Scientific reports, 2018 - nature.com
The traditional classification of hypertensive retinopathy was based on the Keith–Wagener–
Barker (KWB) grading, which is a subjective scaling system, and it is difficult to distinguish …

The effects of graded intraocular pressure challenge on the optic nerve head

N Patel, F McAllister, L Pardon, R Harwerth - Experimental eye research, 2018 - Elsevier
Intraocular pressure (IOP) is an important risk factor for glaucoma, and the response of the
ONH and surrounding tissues to elevated IOP are often investigated to better understand …

Ultrastructural morphology of the optic nerve head in aged and glaucomatous mice

Y Zhu, AC Pappas, R Wang, P Seifert… - … & Visual Science, 2018 - iovs.arvojournals.org
Purpose: To study age-and intraocular pressure–induced changes in the glial lamina of the
murine optic nerve on the ultrastructural level. Methods: Naïve C57bl/6 mice at various ages …

Monitoring retinal responses to acute intraocular pressure elevation in rats with visible light optical coherence tomography

S Pi, TT Hormel, X Wei, W Cepurna, A Camino… - …, 2019 - spiedigitallibrary.org
Elevated intraocular pressure (IOP) is an important risk factor for glaucoma. However, the
role of IOP in glaucoma progression, as well as retinal physiology in general, remains …

Lamina cribrosa capillaries straighten as intraocular pressure increases

BL Brazile, B Yang, S Waxman, P Lam… - … & Visual Science, 2020 - iovs.arvojournals.org
Purpose: The purpose of this study was to visualize the lamina cribrosa (LC) capillaries and
collagenous beams, measure capillary tortuosity (path length over straight end-to-end …

[HTML][HTML] Relationship between intraocular pressure and parameters of obesity in ocular hypertension

MW Ahn, JW Lee, JH Shin, JS Lee - International Journal of …, 2020 - ncbi.nlm.nih.gov
AIM To evaluate the correlation between intraocular pressure (IOP) and various obesity-
related health factors in patients with ocular hypertension in Korea. METHODS A total of 40 …

[HTML][HTML] Optical coherence tomography angiography in mice: quantitative analysis after experimental models of retinal damage

CA Smith, ML Hooper… - … ophthalmology & visual …, 2019 - tvst.arvojournals.org
Purpose: We implemented optical coherence tomography angiography (OCT-A) in mice
to:(1) develop quantitative parameters from OCT-A images,(2) measure the reproducibility of …

Evaluation of macular microvascular density using optical coherence tomography angiography in patients with Posner-Schlossman syndrome

XJ Guo, D Chen, LJ Zhou, SK Luo, Y Lu, JJ Guo - BMC ophthalmology, 2022 - Springer
Background Optical coherence tomography angiography (OCTA) is a novel technology that
provides a noninvasive, dye-less method to visualize the blood vessels of the retina. In the …

[HTML][HTML] Analysis of microvasculature in nonhuman primate macula with acute elevated intraocular pressure using optical coherence tomography angiography

M Choi, SW Kim, TQA Vu, YJ Kim… - … & Visual Science, 2021 - tvst.arvojournals.org
Purpose: To investigate responses of macular capillary vessel area density (VAD) of
superficial and deep retinal vascular plexuses to elevations in intraocular pressure (IOP) in …