It is well acknowledged that muscles that are elongated while activated (ie, eccentric muscle
action) are stronger and require less energy (per unit of force) than muscles that are …

Gaps in our understanding of muscle mechanics demonstrate that the current model is
incomplete. Increasingly, it appears that a role for titin in active muscle contraction might …

Although superthin filaments were inferred from early experiments on muscle, decades
passed before their existence was accepted. Phylogenetic analyses suggest that titin, the …

Since the 1950s, muscle contraction has been explained using a two-filament system in
which actin and myosin exclusively dictate active force in muscle sarcomeres. Decades …

Measuring sarcomere lengths (SLs) in skeletal muscle fibers and myofibrils has traditionally
been done using brightfield and phase contrast (PC) microscopy. This often leads to …