Bioactive compounds and biomedical applications of endophytic fungi: a recent review

AH Hashem, MS Attia, EK Kandil, MM Fawzi… - Microbial Cell …, 2023 - Springer
Human life has been significantly impacted by the creation and spread of novel species of
antibiotic-resistant bacteria and virus strains that are difficult to manage. Scientists and …

Putative anticancer compounds from plant-derived endophytic fungi: a review

M Hridoy, MZH Gorapi, S Noor, NS Chowdhury… - Molecules, 2022 - mdpi.com
Endophytic fungi are microorganisms that exist almost ubiquitously inside the various
tissues of living plants where they act as an important reservoir of diverse bioactive …

Novel secondary metabolites from endophytic fungi: synthesis and biological properties

N Rustamova, K Bozorov, T Efferth, A Yili - Phytochemistry reviews, 2020 - Springer
Plant-associated endophytic fungi are rich sources of novel bioactive and structurally
diverse secondary metabolites and other natural products. Newly synthesized secondary …

Recent advances in search of bioactive secondary metabolites from fungi triggered by chemical epigenetic modifiers

M Xue, X Hou, J Fu, J Zhang, J Wang, Z Zhao, D Xu… - Journal of Fungi, 2023 - mdpi.com
Genomic analysis has demonstrated that many fungi possess essential gene clusters for the
production of previously unobserved secondary metabolites; however, these genes are …

Bioactive Secondary Metabolites of the Genus Diaporthe and Anamorph Phomopsis from Terrestrial and Marine Habitats and Endophytes: 2010–2019

TC Xu, YH Lu, JF Wang, ZQ Song, YG Hou, SS Liu… - Microorganisms, 2021 - mdpi.com
The genus Diaporthe and its anamorph Phomopsis are distributed worldwide in many
ecosystems. They are regarded as potential sources for producing diverse bioactive …

Fungal endophytes: an accessible source of bioactive compounds with potential anticancer activity

N Rai, P Gupta, PK Keshri, A Verma, P Mishra… - Applied Biochemistry …, 2022 - Springer
Endophytes either be bacteria, fungi, or actinomycetes colonize inside the tissue of host
plants without showing any immediate negative effects on them. Among numerous natural …

Natural ten-membered lactones: sources, structural diversity, biological activity, and intriguing future

V Dubovik, A Dalinova, A Berestetskiy - Natural Product Reports, 2024 - pubs.rsc.org
Covering: 2012 to 2022 Ten-membered lactones (TMLs) are an interesting and diverse
group of natural polyketides that are abundant in fungi and, to a lesser extent, in bacteria …

Endophytic Fungi of Native Salvia abrotanoides Plants Reveal High Taxonomic Diversity and Unique Profiles of Secondary Metabolites

Y Teimoori-Boghsani, A Ganjeali, T Cernava… - Frontiers in …, 2020 - frontiersin.org
Endophytic fungi are often embedded in their host's metabolic networks, which can result in
alterations of metabolite production and higher amounts of active compounds in medicinal …

[HTML][HTML] Insights into applications and strategies for discovery of microbial bioactive metabolites

D Maithani, A Sharma, S Gangola, P Chaudhary… - Microbiological …, 2022 - Elsevier
Secondary metabolites of microbial origin are structurally diverse and functionally versatile
compounds that offer selective advantages to the producing organism. Production of these …

Epigenetic Manipulation Induced Production of Immunosuppressive Chromones and Cytochalasins from the Mangrove Endophytic Fungus Phomopsis asparagi DHS …

T Feng, C Wei, X Deng, D Chen, Z Wen, J Xu - Marine Drugs, 2022 - mdpi.com
A mangrove endophytic fungus Phomopsis asparagi DHS-48 was found to be particularly
productive with regard to the accumulation of substantial new compounds in our previous …