[HTML][HTML] Molecular biomarkers in cancer

VK Sarhadi, G Armengol - Biomolecules, 2022 - mdpi.com
Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer,
occurrence of cancer, or patient outcome. They may include germline or somatic genetic …

Radiogenomics: a key component of precision cancer medicine

Z Liu, T Duan, Y Zhang, S Weng, H Xu, Y Ren… - British Journal of …, 2023 - nature.com
Radiogenomics, focusing on the relationship between genomics and imaging phenotypes,
has been widely applied to address tumour heterogeneity and predict immune …

[HTML][HTML] Leveraging transcriptomics for precision diagnosis: Lessons learned from cancer and sepsis

M Tsakiroglou, A Evans, M Pirmohamed - Frontiers in Genetics, 2023 - frontiersin.org
Diagnostics require precision and predictive ability to be clinically useful. Integration of multi-
omic with clinical data is crucial to our understanding of disease pathogenesis and …

Clinicopathological significance of unraveling mitochondrial pathway alterations in non‐small‐cell lung cancer

KL Hertweck, KS Vikramdeo, JN Galeas… - The FASEB …, 2023 - Wiley Online Library
Early detection, accurate monitoring, and therapeutics are major problems in non‐small‐cell
lung cancer (NSCLC) patients. We identified genomic copy number variation of a unique …

Evaluation oncotype DX® 21‐gene recurrence score and clinicopathological parameters: a single institutional experience

A Lashen, MS Toss, W Fadhil, G Oni… - …, 2023 - Wiley Online Library
Aims Oncotype DX recurrence score (RS) is a clinically validated assay, which predicts the
likelihood of disease recurrence in oestrogen receptor‐positive/HER2‐negative …

[HTML][HTML] Blood-based mrna tests as emerging diagnostic tools for personalised medicine in breast cancer

H Čelešnik, U Potočnik - Cancers, 2023 - mdpi.com
Simple Summary Molecular diagnostic tests can facilitate molecular classification of breast
cancer and its clinical management, including prediction, prognosis, and selection of …

[HTML][HTML] MRI radiomics and machine learning for the prediction of oncotype Dx recurrence score in invasive breast cancer

V Romeo, R Cuocolo, L Sanduzzi, V Carpentiero… - Cancers, 2023 - mdpi.com
Simple Summary The preoperative definition of the Oncotype DX recurrence score would be
critical to identify breast cancer patients who could benefit from chemotherapy before …

DCIS: risk assessment in the molecular era

CA Knowlton, RB Jimenez, MS Moran - Seminars in Radiation Oncology, 2022 - Elsevier
Ductal carcinoma in situ (DCIS) represents 20% of all breast cancers. The treatment
paradigm for the majority of patients with DCIS consists of breast-conserving surgery (BCS) …

Assessment of Background Parenchymal Enhancement at Dynamic Contrast-enhanced MRI in Predicting Breast Cancer Recurrence Risk

D Arefan, ML Zuley, WA Berg, L Yang, JH Sumkin… - Radiology, 2024 - pubs.rsna.org
Background Background parenchymal enhancement (BPE) at dynamic contrast-enhanced
(DCE) MRI of cancer-free breasts increases the risk of developing breast cancer; …

[HTML][HTML] Carbonic anhydrase IX-related tumoral hypoxia predicts worse prognosis in breast cancer: A systematic review and meta-analysis

W Numprasit, S Yangngam, J Prasopsiri… - Frontiers in …, 2023 - frontiersin.org
Background Tumoral hypoxia is associated with aggressiveness in many cancers including
breast cancer. However, measuring hypoxia is complicated. Carbonic anhydrase IX (CAIX) …