Thermally dimorphic human fungal pathogens—polyphyletic pathogens with a convergent pathogenicity trait

A Sil, A Andrianopoulos - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Fungi are adept at changing their cell shape and developmental program in response to
signals in their surroundings. Here we focus on a group of evolutionarily related fungal …

Histoplasma capsulatum surmounts obstacles to intracellular pathogenesis

AL Garfoot, CA Rappleye - The FEBS journal, 2016 - Wiley Online Library
The fungal pathogen Histoplasma capsulatum causes respiratory and disseminated
disease, even in immunocompetent hosts. In contrast to opportunistic pathogens, which are …

[HTML][HTML] Comparative genomic analysis of human fungal pathogens causing paracoccidioidomycosis

CA Desjardins, MD Champion, JW Holder… - PLoS …, 2011 - journals.plos.org
Paracoccidioides is a fungal pathogen and the cause of paracoccidioidomycosis, a health-
threatening human systemic mycosis endemic to Latin America. Infection by …

[HTML][HTML] Regulation of Sulphur Assimilation Is Essential for Virulence and Affects Iron Homeostasis of the Human-Pathogenic Mould Aspergillus fumigatus

J Amich, L Schafferer, H Haas, S Krappmann - PLoS pathogens, 2013 - journals.plos.org
Sulphur is an essential element that all pathogens have to absorb from their surroundings in
order to grow inside their infected host. Despite its importance, the relevance of sulphur …

[HTML][HTML] Coccidioides species: A review of basic research: 2022

TN Kirkland, DA Stevens, CY Hung, S Beyhan… - Journal of Fungi, 2022 - mdpi.com
Coccidioides immitis and posadasii are closely related fungal species that cause
coccidioidomycosis. These dimorphic organisms cause disease in immunocompetent as …

[HTML][HTML] The transcriptome analysis of early morphogenesis in Paracoccidioides brasiliensis mycelium reveals novel and induced genes potentially associated to the …

KP Bastos, AM Bailão, CL Borges, FP Faria… - BMC microbiology, 2007 - Springer
Background Paracoccidioides brasiliensis is a human pathogen with a broad distribution in
Latin America. The fungus is thermally dimorphic with two distinct forms corresponding to …

Involvement of an alternative oxidase in oxidative stress and mycelium-to-yeast differentiation in Paracoccidioides brasiliensis

VP Martins, TM Dinamarco, FM Soriani… - Eukaryotic …, 2011 - Am Soc Microbiol
Paracoccidioides brasiliensis is a thermodimorphic human pathogenic fungus that causes
paracoccidioidomycosis (PCM), which is the most prevalent systemic mycosis in Latin …

Exploration of sulfur assimilation of Aspergillus fumigatus reveals biosynthesis of sulfur-containing amino acids as a virulence determinant

J Amich, M Dümig, G O'Keeffe, J Binder… - Infection and …, 2016 - Am Soc Microbiol
Fungal infections are of major relevance due to the increased numbers of
immunocompromised patients, frequently delayed diagnosis, and limited therapeutics. To …

Towards a molecular genetic system for the pathogenic fungus Paracoccidioides brasiliensis

AJ Almeida, JA Carmona, C Cunha, A Carvalho… - Fungal genetics and …, 2007 - Elsevier
We herein report the development of a molecular toolbox for the dimorphic fungus
Paracoccidioides brasiliensis, specifically a more efficient transformation and a gene …

[HTML][HTML] Transcriptional and Proteomic Profiling of Aspergillus flavipes in Response to Sulfur Starvation

ASA El-Sayed, MA Yassin, GS Ali - PLoS One, 2015 - journals.plos.org
Aspergillus flavipes has received considerable interest due to its potential to produce
therapeutic enzymes involved in sulfur amino acid metabolism. In natural habitats, A …