[HTML][HTML] Responsive nanostructure for targeted drug delivery

V Pawar, P Maske, A Khan, A Ghosh, R Keshari… - Journal of …, 2023 - mdpi.com
Currently, intelligent, responsive biomaterials have been widely explored, considering the
fact that responsive biomaterials provide controlled and predictable results in various …

Exchange phenomena in the electron paramagnetic resonance spectra of the nitroxyl and trityl radicals: multifunctional spectroscopy and imaging of local chemical …

VV Khramtsov, AA Bobko, M Tseytlin… - Analytical …, 2017 - ACS Publications
This Feature overviews the basic principles of using stable organic radicals involved in
reversible exchange processes as functional paramagnetic probes. We demonstrate that …

In vivo electron paramagnetic resonance molecular profiling of tumor microenvironment upon tumor progression to malignancy in an animal model of breast cancer

TD Eubank, AA Bobko, EH Hoblitzell… - Molecular Imaging and …, 2024 - Springer
Purpose Hypoxia and acidosis are recognized tumor microenvironment (TME) biomarkers of
cancer progression. Alterations in cancer redox status and metabolism are also associated …

Rapid-scan EPR imaging

SS Eaton, Y Shi, L Woodcock, LA Buchanan… - Journal of Magnetic …, 2017 - Elsevier
In rapid-scan EPR the magnetic field or frequency is repeatedly scanned through the
spectrum at rates that are much faster than in conventional continuous wave EPR. The …

In Vivo Molecular Electron Paramagnetic Resonance-Based Spectroscopy and Imaging of Tumor Microenvironment and Redox Using Functional Paramagnetic …

VV Khramtsov - Antioxidants & redox signaling, 2018 - liebertpub.com
Significance: A key role of the tumor microenvironment (TME) in cancer progression,
treatment resistance, and as a target for therapeutic intervention is increasingly appreciated …

Ligand design of zero-field splitting in trigonal prismatic Ni (II) cage complexes

AJ Campanella, TM Ozvat, JM Zadrozny - Dalton Transactions, 2022 - pubs.rsc.org
Complexes of encapsulated metal ions are promising potential metal-based electron
paramagnetic resonance imaging (EPRI) agents due to zero-field splitting. Herein, we …

Biocompatible Monophosphonated Trityl Spin Probe, HOPE71, for In Vivo Measurement of pO2, pH, and [Pi] by Electron Paramagnetic Resonance Spectroscopy

TD Gluth, M Poncelet, M Gencheva… - Analytical …, 2022 - ACS Publications
Hypoxia, acidosis, and elevated inorganic phosphate concentration are characteristics of the
tumor microenvironment in solid tumors. There are a number of methods for measuring each …

Development of an L-band rapid scan EPR digital console

H Sato-Akaba, M Tseytlin - Journal of Magnetic Resonance, 2019 - Elsevier
The development of a digital console for in-vivo rapid scan electron paramagnetic
resonance (RS-EPR) spectroscopy and imaging is described in detail. The console was …

Continuous wave electron paramagnetic resonance of nitroxide biradicals in fluid solution

SS Eaton, LB Woodcock… - Concepts in Magnetic …, 2018 - Wiley Online Library
Nitroxide biradicals have been prepared with electron‐electron spin‐spin exchange
interaction, J, ranging from weak to very strong. EPR spectra of these biradicals in fluid …

[HTML][HTML] Molecular probes for evaluation of oxidative stress by in vivo EPR spectroscopy and imaging: State-of-the-art and limitations

N Babić, F Peyrot - Magnetochemistry, 2019 - mdpi.com
Oxidative stress, defined as a misbalance between the production of reactive oxygen
species and the antioxidant defenses of the cell, appears as a critical factor either in the …