Diabetes-induced hyperglycemia impairs male reproductive function: a systematic review

CC Maresch, DC Stute, MG Alves… - Human …, 2018 - academic.oup.com
BACKGROUND Hyperglycemia can result from a loss of pancreatic beta-cells or a decline in
their function leading to decreased insulin secretion or may arise from insulin resistance and …

A systematic review on anti-diabetic plant essential oil compounds: Dietary sources, effects, molecular mechanisms, and safety

GR Gandhi, VE Hillary, PJ Antony… - Critical reviews in …, 2024 - Taylor & Francis
Type 2 diabetes mellitus (T2DM) is a multifaceted metabolic syndrome defined through the
dysfunction of pancreatic β-cells driven by a confluence of genetic and environmental …

[HTML][HTML] Complementary and alternative medicine for the treatment of diabetes and associated complications: A review on therapeutic role of polyphenols

P Sharma, YA Hajam, R Kumar, S Rai - Phytomedicine Plus, 2022 - Elsevier
Background: Diabetes is one of the most challenging health problems in 21st century. It is a
group of endocrine-metabolic disorder characterized by high glucose level (hyperglycemia) …

Ameliorative effect of zinc oxide nanoparticles on antioxidants and sperm characteristics in streptozotocin‐induced diabetic rat testes

M Afifi, OA Almaghrabi… - BioMed Research …, 2015 - Wiley Online Library
The present study investigated the impact of zinc oxide nanoparticles (ZnONPs) on the
oxidative status and sperm characteristics in diabetic rat testicular tissue. Forty male albino …

Role of antioxidant natural products in management of infertility: a review of their medicinal potential

S Noh, A Go, DB Kim, M Park, HW Jeon, B Kim - Antioxidants, 2020 - mdpi.com
Infertility, a couple's inability to conceive after one year of unprotected regular intercourse, is
an important issue in the world. The use of natural products in the treatment of infertility has …

The Warburg effect revisited—lesson from the Sertoli cell

PF Oliveira, AD Martins, AC Moreira… - Medicinal research …, 2015 - Wiley Online Library
Otto Warburg observed that cancerous cells prefer fermentative instead of oxidative
metabolism of glucose, although the former is in theory less efficient. Since Warburg's …

Myristic acid defends against testicular oxidative stress, inflammation, apoptosis: Restoration of spermatogenesis, steroidogenesis in diabetic rats

ASM Khalil, N Giribabu, S Yelumalai, H Shahzad… - Life sciences, 2021 - Elsevier
Diabetes mellitus (DM) may lead to testicular-related infertility while Myristic acid (MA) is
beneficial to lower hyperglycaemia. Thus, we hypothesized that MA could protect testes …

Cadmium chloride–induced testicular toxicity in male wistar rats; prophylactic effect of quercetin, and assessment of testicular recovery following cadmium chloride …

VU Nna, GA Ujah, M Mohamed, KB Etim… - Biomedicine & …, 2017 - Elsevier
This study assessed the effect of quercetin (QE) on cadmium chloride (CdCl 2)− induced
testicular toxicity, as well as the effect of withdrawal of CdCl 2 treatment on same. Thirty male …

[HTML][HTML] Omega-3 fatty acid rescues ischaemia/perfusion-induced testicular and sperm damage via modulation of lactate transport and xanthine oxidase/uric acid …

RE Akhigbe, MA Hamed, AF Odetayo… - Biomedicine & …, 2021 - Elsevier
This study aimed to explore the potential antioxidant, anti-inflammatory, and anti-apoptotic
effects of omega 3 fatty acid (Ω-3) in a rat model of testicular torsion/detorsion (T/D). Under …

[HTML][HTML] Pre-diabetes alters testicular PGC1-α/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress

L Rato, AI Duarte, GD Tomas, MS Santos… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Pre-diabetes, a risk factor for type 2 diabetes development, leads to metabolic changes at
testicular level. Peroxisome proliferator-activated receptor γ coactivator 1 α (PGC-1α) and …