Dual role of toll-like receptors in human and experimental asthma models

A Zakeri, M Russo - Frontiers in immunology, 2018 - frontiersin.org
Asthma is a chronic airway inflammatory disease that is influenced by the interplay between
genetic factors and exposure to environmental allergens, microbes, or microbial products …

Association of single nucleotide polymorphisms in toll-like receptor genes with asthma risk: a systematic review and meta-analysis

K Tizaoui, W Kaabachi, K Hamzaoui… - Allergy, asthma & …, 2015 - synapse.koreamed.org
Purpose Asthma is a complex disease, with contributions from multiple genes, various
genetic backgrounds, and environmental factors. Many human epidemiological studies have …

Association of polymorphisms in TLR2 and TLR4 with asthma risk: an update meta-analysis

J Zhao, H Shang, X Cao, Y Huang, X Fang, S Zhang… - Medicine, 2017 - journals.lww.com
Background: Several epidemiological studies have focused on the association between
polymorphisms in toll-like receptors (TLRs) and asthma. However, the results remained …

Bet v 1 triggers antiviral‐type immune signalling in birch‐pollen‐allergic individuals

L Wisgrill, N Fyhrquist, J Ndika… - Clinical & …, 2022 - Wiley Online Library
Background In allergic patients, clinical symptoms caused by pollen remind of symptoms
triggered by viral respiratory infections, which are also the main cause of asthmatic …

mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo

F Zeyer, B Mothes, C Will, M Carevic, J Rottenberger… - PLoS …, 2016 - journals.plos.org
Asthma is the most common chronic disease in childhood. Although several therapeutic
options are currently available to control the symptoms, many drugs have significant side …

Genetic association of TLR 4 Asp299Gly, TLR 4 Thr399Ile, and CD 14 C‐159T polymorphisms with the risk of severe RSV infection: a meta‐analysis

J Zhou, X Zhang, S Liu, Z Wang, Q Chen… - Influenza and Other …, 2016 - Wiley Online Library
Respiratory syncytial virus (RSV) is the most frequent cause of hospitalization in infants
worldwide. It is recognized by Toll‐like receptor 4 (TLR 4) and cluster of differentiation 14 …

LncRNA ANRIL promotes autophagy activation through miR-16-5p/TLR4 axis in allergic rhinitis

MQ Wang, XH Zhu, K Liu, XY Tian… - American Journal of …, 2022 - journals.sagepub.com
Background Allergic rhinitis (AR) is an allergic disease of nasal mucosa. LncRNAs are key
modulators affecting AR development. Neverthelss, the impact of lncRNA ANRIL in AR is not …

Interaction of CD14 haplotypes and soluble CD14 on pulmonary function in agricultural workers

TD LeVan, LM Smith, AJ Heires, TR Mikuls, JL Meza… - Respiratory …, 2017 - Springer
Background Agricultural environments are contaminated with organic dusts containing
bacterial components. Chronic inhalation of organic dusts is implicated in respiratory …

Association of TLR4 gene rs4986790 and rs4986791 polymorphisms with asthma susceptibility: meta-analysis and trial sequential analysis

N Guo, H Tian, T Song, Y Peng - Annals of Saudi Medicine, 2024 - annsaudimed.net
BACKGROUND: The current understanding of the correlation between TLR4 gene (toll-like
receptor 4) rs4986790 and rs4986791 polymorphisms and asthma susceptibility is …

Association of toll-like receptor polymorphisms with nasal polyposis

GG Kesici, S Kargın Kaytez, T Özdaş… - Ear, Nose & Throat …, 2021 - journals.sagepub.com
Nasal polyposis is a disease characterized with chronic inflammation of the nasal mucosa.
Toll-like receptors (TLRs) are defined as essential receptors of the innate immune system …