TCM Database@Taiwan: The World's Largest Traditional Chinese Medicine Database for Drug Screening In Silico
CYC Chen - PloS one, 2011 - journals.plos.org
Rapid advancing computational technologies have greatly speeded up the development of
computer-aided drug design (CADD). Recently, pharmaceutical companies have …
computer-aided drug design (CADD). Recently, pharmaceutical companies have …
Virus-mPLoc: a fusion classifier for viral protein subcellular location prediction by incorporating multiple sites
HB Shen, KC Chou - Journal of Biomolecular Structure and …, 2010 - Taylor & Francis
Abstract Knowledge of the subcellular localization of viral proteins in a host cell or virus-
infected cell is very important because it is closely related to their destructive tendencies and …
infected cell is very important because it is closely related to their destructive tendencies and …
Potential drug targets on insomnia and intervention effects of Jujuboside A through metabolic pathway analysis as revealed by UPLC/ESI-SYNAPT-HDMS coupled …
X Wang, B Yang, A Zhang, H Sun, G Yan - Journal of proteomics, 2012 - Elsevier
Potential metabolites from the metabolic pathways could be therapeutic targets and useful
for the discovery of broad spectrum drugs. UPLC/ESI-SYNAPT-HDMS coupled with pattern …
for the discovery of broad spectrum drugs. UPLC/ESI-SYNAPT-HDMS coupled with pattern …
Anti-infectious bronchitis virus (IBV) activity of 1, 8-cineole: effect on nucleocapsid (N) protein
In the present study, anti-IBV (infectious bronchitis virus) activity of 1, 8-cineole was studied
by MTT assay, as well as docking and molecular dynamic (MD) simulations. The CC50 of 1 …
by MTT assay, as well as docking and molecular dynamic (MD) simulations. The CC50 of 1 …
Two birds with one stone? Possible dual-targeting H1N1 inhibitors from traditional Chinese medicine
SS Chang, HJ Huang, CYC Chen - PLoS Computational Biology, 2011 - journals.plos.org
The H1N1 influenza pandemic of 2009 has claimed over 18,000 lives. During this pandemic,
development of drug resistance further complicated efforts to control and treat the …
development of drug resistance further complicated efforts to control and treat the …
Structure-based and ligand-based drug design for HER 2 receptor
HJ Huang, KJ Lee, HW Yu, CY Chen… - Journal of …, 2010 - Taylor & Francis
Human epidermal growth factor receptor 2, HER2, is a commonly over-expressed tyrosine
kinase receptor found in many types of carcinoma. Despite that there are several HER2 …
kinase receptor found in many types of carcinoma. Despite that there are several HER2 …
Applications of docking and molecular dynamic studies on the search for new drugs against the biological warfare agents Bacillus anthracis and Yersinia pestis
T Celmar Costa Franca… - … -Aided Drug Design, 2013 - ingentaconnect.com
The fear of biological warfare agents (BWA) use by terrorists is the major concern of the
security agencies and health authorities worldwide today. The non-existence of vaccines or …
security agencies and health authorities worldwide today. The non-existence of vaccines or …
Comparison of binding interactions of lomefloxacin to serum albumin and serum transferrin by resonance light scattering and fluorescence quenching methods
H Vahedian-Movahed, MR Saberi… - Journal of Biomolecular …, 2011 - Taylor & Francis
The interaction between lomefloxacin (LMF) and two drug carrier proteins, human serum
albumin (HSA) and serum transferrin (TF), were studied and compared by fluorescence …
albumin (HSA) and serum transferrin (TF), were studied and compared by fluorescence …
Potent inhibitor design against H1N1 swine influenza: structure-based and molecular dynamics analysis for M2 inhibitors from traditional Chinese medicine database
CH Lin, TT Chang, MF Sun, HY Chen… - Journal of …, 2011 - Taylor & Francis
The rapid spread of influenza virus subtype H1N1 poses a great threat to million lives
worldwide. To search for new anti-influenza compounds, we performed molecular docking …
worldwide. To search for new anti-influenza compounds, we performed molecular docking …
Investigations with spectroscopy, zeta potential and molecular modeling of the non-cooperative behaviour between cyclophosphamide hydrochloride and aspirin …
Z Omidvar, K Parivar, H Sanee… - Journal of …, 2011 - Taylor & Francis
The interaction between cyclophosphamide hydrochloride (CYC) and aspirin (ASA) with
human serum albumin (HSA) was studied by various kind of spectroscopic, ζ potential and …
human serum albumin (HSA) was studied by various kind of spectroscopic, ζ potential and …