EGFR targeting for cancer therapy: Pharmacology and immunoconjugates with drugs and nanoparticles
E da Silva Santos, KAB Nogueira… - International journal of …, 2021 - Elsevier
The epidermal growth factor receptor (EGFR) belongs to the tyrosine kinase receptors family
and is present in the epithelial cell membrane. Its endogenous activation occurs through the …
and is present in the epithelial cell membrane. Its endogenous activation occurs through the …
Recent developments in innovative magnetic nanoparticles-based immunoassays: from improvement of conventional immunoassays to diagnosis of COVID-19
During the ongoing COVID-19 pandemic, the development of point-of-care (POC) detection
with high sensitivity and rapid detection time is urgently needed to prevent transmission of …
with high sensitivity and rapid detection time is urgently needed to prevent transmission of …
Determination of DNA and RNA methylation in circulating tumor cells by mass spectrometry
DNA methylation (5-methylcytosine, 5-mC) is the best characterized epigenetic mark that
has regulatory roles in diverse biological processes. Recent investigation of RNA …
has regulatory roles in diverse biological processes. Recent investigation of RNA …
Magnetically Modulated Differential Quartz Crystal Microbalances for Rapid, Ultrasensitive, and Direct Probing of Prostate-Specific Antigens Conjugated with Magnetic …
D Chen, Y Wen, P Li, Y Wang, T Dong - ACS sensors, 2023 - ACS Publications
The occurrence and development of diseases are closely related to overexpression of
specific biomarkers in the serum of patients. Rapid and sensitive biomarker detection is …
specific biomarkers in the serum of patients. Rapid and sensitive biomarker detection is …
Sensing of survivin mRNA in malignant astrocytes using graphene oxide nanocarrier-supported oligonucleotide molecular beacons
M Stobiecka, B Dworakowska, S Jakiela… - Sensors and Actuators B …, 2016 - Elsevier
While a significant progress has recently been made in therapy of many cancers, the cure for
some high grade cancers, such as the astrocytic cancers, remains elusive. In the latter case …
some high grade cancers, such as the astrocytic cancers, remains elusive. In the latter case …
Recent development of nanomaterials-based cytosensors for the detection of circulating tumor cells
ZF Sun, Y Chang, N Xia - Biosensors, 2021 - mdpi.com
The accurate analysis of circulating tumor cells (CTCs) holds great promise in early
diagnosis and prognosis of cancers. However, the extremely low abundance of CTCs in …
diagnosis and prognosis of cancers. However, the extremely low abundance of CTCs in …
Efficient capture and simple quantification of circulating tumor cells using quantum dots and magnetic beads
Circulating tumor cells (CTCs) are valuable biomarkers for monitoring the status of cancer
patients and drug efficacy. However, the number of CTCs in the blood is extremely low, and …
patients and drug efficacy. However, the number of CTCs in the blood is extremely low, and …
Critical parameters for particle-based pulmonary delivery of chemotherapeutics
Targeted delivery of chemotherapeutics through the respiratory system is a potential
approach to improve drug accumulation in the lung tumor, while decreasing their negative …
approach to improve drug accumulation in the lung tumor, while decreasing their negative …
A novel sandwich-like cytosensor based on aptamers-modified magnetic beads and carbon dots/cobalt oxyhydroxide nanosheets for circulating tumor cells detection
C Shen, L Zhong, L Xiong, C Liu, L Yu, X Chu… - Sensors and Actuators B …, 2021 - Elsevier
As a part of" tumor fluid biopsy", circulating tumor cells (CTCs) contain enormous tumor
information, so the detection of CTCs is very helpful in clinical diagnosis and therapy. Here …
information, so the detection of CTCs is very helpful in clinical diagnosis and therapy. Here …
β-Cyclodextrin coated and folic acid conjugated magnetic halloysite nanotubes for targeting and isolating of cancer cells
X Li, J Chen, H Liu, Z Deng, J Li, T Ren, L Huang… - Colloids and Surfaces B …, 2019 - Elsevier
The study developed a simple, effective and inexpensive strategy for capturing, enriching
and detecting circulating tumor cells (CTCs) by using folic acid (FA) as the targeting …
and detecting circulating tumor cells (CTCs) by using folic acid (FA) as the targeting …