[HTML][HTML] Antioxidant, anti-inflammatory, anti-menopausal, and anti-cancer effects of lignans and their metabolites

WY Jang, MY Kim, JY Cho - International journal of molecular sciences, 2022 - mdpi.com
Since chronic inflammation can be seen in severe, long-lasting diseases such as cancer,
there is a high demand for effective methods to modulate inflammatory responses. Among …

The what and who of dietary lignans in human health: Special focus on prooxidant and antioxidant effects

S Soleymani, S Habtemariam, R Rahimi… - Trends in Food Science & …, 2020 - Elsevier
Background Lignans are large group of polyphenols that are formed by the coupling of two
coniferyl alcohol residues. Based on their origin, lignans are broadly grouped into plant …

[HTML][HTML] Insights into antioxidant activities and anti-skin-aging potential of callus extract from Centella asiatica (L.)

V Buranasudja, D Rani, A Malla, K Kobtrakul… - Scientific Reports, 2021 - nature.com
Formation of oxidative stress in dermal fibroblasts plays crucial roles in aging processes of
skin. The use of phytochemicals that can promote capacity of fibroblasts to combat oxidative …

[HTML][HTML] Antifungal Activity of Human Cathelicidin LL-37, a Membrane Disrupting Peptide, by Triggering Oxidative Stress and Cell Cycle Arrest in Candida auris

IA Rather, JSM Sabir, AH Asseri, S Ali - Journal of Fungi, 2022 - mdpi.com
Candida auris, an evolving multidrug-resistant pathogenic yeast, is known for causing
severe invasive infections associated with high mortality rates in hospitalized individuals …

[HTML][HTML] Empagliflozin alleviates renal inflammation and oxidative stress in streptozotocin-induced diabetic rats partly by repressing HMGB1-TLR4 receptor axis

ZA Jigheh, AG Haghjo, H Argani… - Iranian journal of …, 2019 - ncbi.nlm.nih.gov
Objective (s): Empagliflozin, a sodium-glucose cotransporter-2 (SGLT-2) inhibitor,
possesses verified anti-inflammatory and anti-oxidative stress effects against diabetic …

[HTML][HTML] Lignans as pharmacological agents in disorders related to oxidative stress and inflammation: chemical synthesis approaches and biological activities

DI Osmakov, AP Kalinovskii, OA Belozerova… - International journal of …, 2022 - mdpi.com
Plant lignans exhibit a wide range of biological activities, which makes them the research
objects of potential use as therapeutic agents. They provide diverse naturally-occurring …

[HTML][HTML] Terpenoid-Rich Extract of Dillenia indica L. Bark Displays Antidiabetic Action in Insulin-Resistant C2C12 Cells and STZ-Induced Diabetic Mice by Attenuation …

BR Song, MB Alam, SH Lee - Antioxidants, 2022 - mdpi.com
Insulin resistance (IR) plays a key role in the pathogenesis and clinical outcome of patients
with multiple diseases and diabetes. In this study, we examined the antidiabetic effects of a …

[HTML][HTML] Ethanol-mediated stress promotes autophagic survival and aggressiveness of colon cancer cells via activation of Nrf2/HO-1 pathway

C Cernigliaro, A D'Anneo, D Carlisi, M Giuliano… - Cancers, 2019 - mdpi.com
Epidemiological studies suggest that chronic alcohol consumption is a lifestyle risk factor
strongly associated with colorectal cancer development and progression. The aim of the …

[HTML][HTML] Natural antioxidant and anti-inflammatory compounds in foodstuff or medicinal herbs inducing heme oxygenase-1 expression

D Hahn, SH Shin, JS Bae - Antioxidants, 2020 - mdpi.com
Heme oxygenase-1 (HO-1) is an inducible antioxidant enzyme that catalyzes heme group
degradation. Decreased level of HO-1 is correlated with disease progression, and HO-1 …

[HTML][HTML] A Preliminary Assessment of the Nutraceutical Potential of Acai Berry (Euterpe sp.) as a Potential Natural Treatment for Alzheimer's Disease

MN ALNasser, IR Mellor, WG Carter - Molecules, 2022 - mdpi.com
Alzheimer's disease (AD) is characterised by progressive neuronal atrophy and the loss of
neuronal function as a consequence of multiple pathomechanisms. Current AD treatments …