Abstract Direct-to-consumer (DTC) genetic testing emerged in the early 2000s as a means of
allowing consumers to access information on their genetics without the involvement of a …

Despite the plethora of empirical studies conducted to date, debate continues about whether
and to what extent results should be returned to participants of genomic research. We aimed …

Background The concept of digital twins has great potential for transforming the existing
health care system by making it more personalized. As a convergence of health care …

Researchers and clinicians refer to outcomes of genomic testing that extend beyond clinical
utility as 'personal utility'. No systematic delineation of personal utility exists, making it …

Background The use of genome-wide (whole genome or exome) sequencing for population-
based newborn screening presents an opportunity to detect and treat or prevent many more …

PURPOSE In the era of personalized medicine, physicians rely on their understanding of
clinical utility to assess the value of rapidly evolving genetic and genomic tests. Current …

Importance Population screening for medically relevant genomic variants that cause
diseases such as hereditary cancer and cardiovascular disorders is increasing to facilitate …

Given the limited therapeutic options for most rare diseases diagnosed through genomic
sequencing (GS) and the proportion of patients who remain undiagnosed even after GS, it is …

BACKGROUND AND OBJECTIVES: There is interest in applying genomic sequencing (GS)
to newborns' clinical care. Here we explore parents' and clinicians' attitudes toward and …

This article characterizes the opinions of patients and family members of patients
undergoing clinical genomic-based testing regarding the return of incidental findings from …