Nanobio silver: its interactions with peptides and bacteria, and its uses in medicine

S Eckhardt, PS Brunetto, J Gagnon, M Priebe… - Chemical …, 2013 - ACS Publications
Silver, known in metallic form since antiquity, has very early been recognized by mankind for
its antimicrobial properties, a phenomenon observed, for example, in the context of drinking …

The ins and outs of RND efflux pumps in Escherichia coli

J Anes, MP McCusker, S Fanning… - Frontiers in microbiology, 2015 - frontiersin.org
Infectious diseases remain one of the principal causes of morbidity and mortality in the
world. Relevant authorities including the WHO and CDC have expressed serious concern …

Similarities and differences between silver ions and silver in nanoforms as antibacterial agents

A Kędziora, M Speruda, E Krzyżewska, J Rybka… - International journal of …, 2018 - mdpi.com
Silver is considered as antibacterial agent with well-known mode of action and bacterial
resistance against it is well described. The development of nanotechnology provided …

Molecular basis of active copper resistance mechanisms in Gram-negative bacteria

K Bondarczuk, Z Piotrowska-Seget - Cell biology and toxicology, 2013 - Springer
Copper is a metallic element that is crucial for cell metabolism; however, in extended
concentrations, it is toxic for all living organisms. The dual nature of copper has forced …

RND efflux pumps in Gram-negative bacteria; regulation, structure and role in antibiotic resistance

AL Colclough, I Alav, EE Whittle, HL Pugh… - Future …, 2020 - Taylor & Francis
Rresistance-nodulation-division (RND) efflux pumps in Gram-negative bacteria remove
multiple, structurally distinct classes of antimicrobials from inside bacterial cells therefore …

Size-dependent antimicrobial effects of novel palladium nanoparticles

CP Adams, KA Walker, SO Obare, KM Docherty - PloS one, 2014 - journals.plos.org
Investigating the interactions between nanoscale materials and microorganisms is crucial to
provide a comprehensive, proactive understanding of nanomaterial toxicity and explore the …

Structural and functional diversity of resistance–nodulation–cell division transporters

PA Klenotic, MA Moseng, CE Morgan, EW Yu - Chemical reviews, 2020 - ACS Publications
Multidrug resistant (MDR) bacteria are a global threat with many common infections
becoming increasingly difficult to eliminate. While significant effort has gone into the …

Bacterial multidrug efflux transporters

JA Delmar, CC Su, EW Yu - Annual review of biophysics, 2014 - annualreviews.org
Infections caused by bacteria are a leading cause of death worldwide. Although antibiotics
remain a key clinical therapy, their effectiveness has been severely compromised by the …

Switch or funnel: how RND-type transport systems control periplasmic metal homeostasis

EH Kim, DH Nies, MM McEvoy… - Journal of bacteriology, 2011 - Am Soc Microbiol
Bacteria have evolved several transport mechanisms to maintain metal homeostasis and to
detoxify the cell. One mechanism involves an RND (r esistance-n odulation-cell d ivision …

Evolution of a heavy metal homeostasis/resistance island reflects increasing copper stress in enterobacteria

BM Staehlin, JG Gibbons, A Rokas… - Genome biology and …, 2016 - academic.oup.com
Copper homeostasis in bacteria is challenged by periodic elevation of copper levels in the
environment, arising from both natural sources and human inputs. Several mechanisms …