Cannabinoids and the expanded endocannabinoid system in neurological disorders
L Cristino, T Bisogno, V Di Marzo - Nature Reviews Neurology, 2020 - nature.com
Anecdotal evidence that cannabis preparations have medical benefits together with the
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …
A conceptual framework for astrocyte function
The participation of astrocytes in brain computation was hypothesized in 1992, coinciding
with the discovery that these cells display a form of intracellular Ca2+ signaling sensitive to …
with the discovery that these cells display a form of intracellular Ca2+ signaling sensitive to …
Astrocyte function from information processing to cognition and cognitive impairment
Astrocytes serve important roles that affect recruitment and function of neurons at the local
and network levels. Here we review the contributions of astrocyte signaling to synaptic …
and network levels. Here we review the contributions of astrocyte signaling to synaptic …
[HTML][HTML] Behaviorally consequential astrocytic regulation of neural circuits
Astrocytes are a large and diverse population of morphologically complex cells that exist
throughout nervous systems of multiple species. Progress over the last two decades has …
throughout nervous systems of multiple species. Progress over the last two decades has …
Glucose metabolism links astroglial mitochondria to cannabinoid effects
D Jimenez-Blasco, A Busquets-Garcia… - Nature, 2020 - nature.com
Astrocytes take up glucose from the bloodstream to provide energy to the brain, thereby
allowing neuronal activity and behavioural responses,,,–. By contrast, astrocytes are under …
allowing neuronal activity and behavioural responses,,,–. By contrast, astrocytes are under …
Diversity and specificity of astrocyte–neuron communication
CA Durkee, A Araque - Neuroscience, 2019 - Elsevier
Astrocytes are emerging as important players in synaptic function, and, consequently, on
brain function and animal behavior. According to the Tripartite Synapse concept, astrocytes …
brain function and animal behavior. According to the Tripartite Synapse concept, astrocytes …
Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents
J Wahis, A Baudon, F Althammer, D Kerspern… - Nature …, 2021 - nature.com
Oxytocin (OT) orchestrates social and emotional behaviors through modulation of neural
circuits. In the central amygdala, the release of OT modulates inhibitory circuits and, thereby …
circuits. In the central amygdala, the release of OT modulates inhibitory circuits and, thereby …
G-protein-coupled receptors in astrocyte–neuron communication
Astrocytes, a major type of glial cell, are known to play key supportive roles in brain function,
contributing to ion and neurotransmitter homeostasis, maintaining the blood–brain barrier …
contributing to ion and neurotransmitter homeostasis, maintaining the blood–brain barrier …
The role of astrocyte structural plasticity in regulating neural circuit function and behavior
Brain circuits undergo substantial structural changes during development, driven by the
formation, stabilization, and elimination of synapses. Synaptic connections continue to …
formation, stabilization, and elimination of synapses. Synaptic connections continue to …
[HTML][HTML] Calcium signaling in astrocytes and gliotransmitter release
Glia are as numerous in the brain as neurons and widely known to serve supportive roles
such as structural scaffolding, extracellular ionic and neurotransmitter homeostasis, and …
such as structural scaffolding, extracellular ionic and neurotransmitter homeostasis, and …