The role of European healthcare databases for post-marketing drug effectiveness, safety and value evaluation: where does Italy stand?

G Trifirò, R Gini, F Barone-Adesi, E Beghi, A Cantarutti… - Drug Safety, 2019 - Springer
Enormous progress has been made globally in the use of evidence derived from patients'
clinical information as they access their routine medical care. The value of real-world data …

Risks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four …

M Alexander, AK Loomis, J Van Der Lei… - BMC medicine, 2019 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) is a common condition that
progresses in some patients to steatohepatitis (NASH), cirrhosis and hepatocellular …

Real-world data reveal a diagnostic gap in non-alcoholic fatty liver disease

M Alexander, AK Loomis, J Fairburn-Beech… - BMC medicine, 2018 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver
disease worldwide. It affects an estimated 20% of the general population, based on cohort …

Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults

M Alexander, AK Loomis, J van der Lei… - bmj, 2019 - bmj.com
Objective To estimate the risk of acute myocardial infarction (AMI) or stroke in adults with
non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH). Design …

Algorithms to identify COPD in health systems with and without access to ICD coding: a systematic review

H Gothe, S Rajsic, D Vukicevic, T Schoenfelder… - BMC health services …, 2019 - Springer
Background Chronic obstructive pulmonary disease (COPD) causes significant morbidity
and mortality worldwide. Estimation of incidence, prevalence and disease burden through …

The economic burden of disease in France from the National Health Insurance Perspective: the healthcare expenditures and conditions mapping used to prepare the …

A Rachas, C Gastaldi-Ménager, P Denis… - Medical care, 2022 - journals.lww.com
Background: Identifying the most frequently treated and the costliest health conditions is
essential for prioritizing actions to improve the resilience of health systems. Objectives …

Survival and factors predicting mortality after major and minor lower-extremity amputations among patients with diabetes: a population-based study using health …

S Cascini, N Agabiti, M Davoli, L Uccioli… - BMJ Open Diabetes …, 2020 - drc.bmj.com
Introduction The aim of the study was to identify the sociodemographic and clinical factors
associated with death after the first lower-extremity amputation (LEA), minor and major …

Pregnancy outcomes and maternal characteristics in women with pregestational and gestational diabetes: a retrospective study on 206,917 singleton live births

E Gualdani, G Di Cianni, M Seghieri, P Francesconi… - Acta Diabetologica, 2021 - Springer
Aims To examine risk of adverse pregnancy outcomes, mothers' characteristics and
incidence rate over time of pregestational type 1 (T1D), type 2 (T2D) or gestational diabetes …

Prevalence of chronic medical conditions in Switzerland: exploring estimates validity by comparing complementary data sources

U Zellweger, M Bopp, BM Holzer, S Djalali, V Kaplan - BMC public health, 2014 - Springer
Background Prevalence estimates of chronic medical conditions and their multiples
(multimorbidity) in the general population are scarce and often rather speculative in …

[HTML][HTML] Data extraction and management in networks of observational health care databases for scientific research: a comparison of EU-ADR, OMOP, Mini-Sentinel …

R Gini, M Schuemie, J Brown, P Ryan, E Vacchi… - Egems, 2016 - ncbi.nlm.nih.gov
Conclusion: Using our conceptual framework we found several areas that would benefit from
research to identify optimal standards for production of empirical knowledge from existing …