Candida auris Genetics and Emergence

A Chowdhary, K Jain, N Chauhan - Annual Review of …, 2023 - annualreviews.org
Candida auris is a multidrug-resistant fungal pathogen that presents a serious threat to
global human health. Since the first reported case in 2009 in Japan, C. auris infections have …

Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Nikkomycin Z—ready to meet the promise?

DJ Larwood - Journal of Fungi, 2020 - mdpi.com
Nikkomycin Z (NikZ) has fungicidal activity against some fungal species which currently
requires patients to endure chronic therapy, sometimes for years. This review highlights …

Coumarins: antifungal effectiveness and future therapeutic scope

JS Prusty, A Kumar - Molecular diversity, 2020 - Springer
The antifungals that are in current clinical practice have a high occurrence of a side effect
and multidrug resistance (MDR). Researchers across the globe are trying to develop a …

Antifungal resistance, metabolic routes as drug targets, and new antifungal agents: an overview about endemic dimorphic fungi

JA Parente-Rocha, AM Bailão… - Mediators of …, 2017 - Wiley Online Library
Diseases caused by fungi can occur in healthy people, but immunocompromised patients
are the major risk group for invasive fungal infections. Cases of fungal resistance and the …

Antifungal therapy for systemic mycosis and the nanobiotechnology era: improving efficacy, biodistribution and toxicity

ACO Souza, AC Amaral - Frontiers in Microbiology, 2017 - frontiersin.org
Fungal diseases have been emerging as an important public health problem worldwide with
the increase in host predisposition factors due to immunological dysregulations …

Identification of mycoses in developing countries

A Arastehfar, BL Wickes, M Ilkit, DH Pincus… - Journal of Fungi, 2019 - mdpi.com
Extensive advances in technology offer a vast variety of diagnostic methods that save time
and costs, but identification of fungal species causing human infections remains challenging …

Emergomycosis, an emerging systemic mycosis in immunocompromised patients: Current trends and future prospects

A Samaddar, A Sharma - Frontiers in Medicine, 2021 - frontiersin.org
Recently, the global emergence of emergomycosis, a systemic fungal infection caused by a
novel dimorphic fungus Emergomyces species has been observed among …

Screening of Pandemic Response Box Library Reveals the High Activity of Olorofim against Pathogenic Sporothrix Species

LP Borba-Santos, R Rollin-Pinheiro, Y da Silva Fontes… - Journal of Fungi, 2022 - mdpi.com
The increase in the prevalence and severity of fungal infections and the resistance to
available antifungals highlights the imperative need for novel therapeutics and the search …

Nikkomycin Z for the treatment of experimental sporotrichosis caused by Sporothrix brasiliensis

VR Poester, LS Munhoz, DA Stevens, AM Melo… - Mycoses, 2023 - Wiley Online Library
Sporotrichosis caused by Sporothrix brasiliensis is a global emergent infectious disease.
Due to the scarcity of therapeutic options for fungal diseases, new antifungals are urgently …