Inflammation is one of the most characteristic features of chronic liver disease of viral,
alcoholic, fatty, and autoimmune origin. Inflammation is typically present in all disease …

Hepatic cirrhosis and hepatocellular carcinoma (HCC) are the most common causes of
death in patients with chronic liver disease. Chronic liver injury of virtually any etiology …

Background and aims Liver fibrosis is a wound-healing response that disrupts the liver
architecture and function by replacing functional parenchyma with scar tissue. Recent …

We investigated whether ancestral liver damage leads to heritable reprogramming of
hepatic wound healing in male rats. We found that a history of liver damage corresponds …

Whether bone marrow modulates systemic metabolism remains unknown. Our recent study
suggested that myeloid-derived growth factor (MYDGF) improves insulin resistance. Here …

Tissue homeostasis requires an effective, limited wound-healing response to injury. In
chronic disease, failure to regenerate parenchymal tissue leads to the replacement of lost …

Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor,
which stimulates cell proliferation and exhibits a proliferation-specific expression pattern …

Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor
and is also intimately involved in tumorigenesis. FOXM1 stimulates cell proliferation and cell …

Diabetic foot ulcers (DFU) are a serious complication of diabetes mellitus and associated
with reduced quality of life and high mortality rate. DFUs are characterized by a deregulated …

c-Rel is a member of the nuclear factor κB (NF-κB) transcription factor family. Unlike other NF-
κB proteins that are expressed in a variety of cell types, high levels of c-Rel expression are …