Lipid-based nanovesicular drug delivery systems

T Limongi, F Susa, M Marini, M Allione, B Torre… - Nanomaterials, 2021 - mdpi.com
In designing a new drug, considering the preferred route of administration, various
requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a …

Proniosomes derived niosomes: recent advancements in drug delivery and targeting

M Khatoon, KU Shah, FU Din, SU Shah… - Drug …, 2017 - Taylor & Francis
Vesicular drug delivery systems have gained wide attention in the field of nanotechnology.
Among them proniosomes become the superior over other vesicular carriers. Proniosomes …

Formulation and optimization of lacidipine loaded niosomal gel for transdermal delivery: in-vitro characterization and in-vivo activity

M Qumbar, SS Imam, J Ali, J Ahmad, A Ali - Biomedicine & …, 2017 - Elsevier
The aim of the present research work is to formulate lacidipine (LAC) loaded niosomes
formulation for the management of hypertension by thin film hydration technique. The …

Optimization, physicochemical characterization, and antimicrobial activity of a novel simvastatin nano-niosomal gel against E. coli and S. aureus

I Akbarzadeh, M Keramati, A Azadi, E Afzali… - Chemistry and Physics …, 2021 - Elsevier
Niosomes, as a kind of drug delivery system, is widely used for the topical delivery of
lipophilic drugs. Optimization of niosomes plays an essential role in enhancing their …

Compritol-based nanostrucutured lipid carriers (NLCs) for augmentation of zolmitriptan bioavailability via the transdermal route: in vitro optimization, ex vivo …

DH Hassan, JN Shohdy, DA El-Setouhy… - Pharmaceutics, 2022 - mdpi.com
Migraine is a severe neurovascular disease manifested mainly as unilateral throbbing
headaches. Triptans are agonists for serotonin receptors. Zolmitriptan (ZMP) is a …

Formulation of novel niosomal repaglinide chewable tablets using coprocessed excipients: in vitro characterization, optimization and enhanced hypoglycemic activity …

SA Fouad, MH Teaima, MI Gebril, FI Abd Allah… - Drug Delivery, 2023 - Taylor & Francis
Repaglinide (RPG), a monotherapy insulin secretagogue used to treat diabetes mellitus-
type II yet, it suffers from poor water solubility and variable bioavailability (∼ 50%) due to …

[HTML][HTML] Spanlastic-laden in situ gel as a promising approach for ocular delivery of Levofloxacin: In-vitro characterization, microbiological assessment, corneal …

OA Agha, GNS Girgis, MMA El-Sokkary… - International Journal of …, 2023 - Elsevier
The objective of this study was to encapsulate the antibacterial drug levofloxacin
hemihydrate (LF) into spanlastics (SLs) followed by incorporation into gelrite in situ gel to …

[PDF][PDF] Emulgel-novel topical drug delivery system-a comprehensive review

D Kumar, J Singh, M Antil, V Kumar - International journal of …, 2016 - researchgate.net
Emulgel systems are currently of attention to the pharmaceutical scientists because of their
substantial potential to act as drug delivery vehicle by incorporating a broad range of drug …

Design and optimization of cranberry extract loaded bile salt augmented liposomes for targeting of MCP-1/STAT3/VEGF signaling pathway in DMN-intoxicated liver in …

S M. Soliman, S Mosallam, MA Mamdouh… - Drug Delivery, 2022 - Taylor & Francis
Cranberry extract (CBE) is a major source of the antioxidant polyphenolics but suffers from
limited bioavailability. The goal of this research was to encapsulate the nutraceutical (CBE) …

Quality-by-design in pharmaceutical development: From current perspectives to practical applications

B Kovács, B KOVÁCS-DEÁK… - Acta …, 2021 - hrcak.srce.hr
Sažetak Current pharmaceutical research directions tend to follow a systematic approach in
the field of applied research and development. The concept of quality-by-design (QbD) has …