MicroRNAs (miRNAs) are a large family of post-transcriptional regulators of gene expression
that are∼ 21 nucleotides in length and control many developmental and cellular processes …

Long-lasting forms of synaptic plasticity and memory are dependent on new protein
synthesis. Recent advances obtained from genetic, physiological, pharmacological, and …

Background The genetic cause of intellectual disability in most patients is unclear because
of the absence of morphological clues, information about the position of such genes, and …

Unraveling the molecular mechanisms governing long-term synaptic plasticity is a key to
understanding how the brain stores information in neural circuits and adapts to a changing …

Rapid input-restricted change in gene expression is an important aspect of synaptic
plasticity requiring complex mechanisms of post-transcriptional mRNA trafficking and …

Type 2 diabetes mellitus (DM) is a common metabolic disorder predisposing to diabetic
cardiomyopathy and atherosclerotic cardiovascular disease (CVD), which could lead to …

MicroRNAs (miRNAs) are emerging as key modulators of post-transcriptional gene
regulation in a plethora of tissues, including the nervous system. Recent evidence points to …

A class of small, non-coding transcripts called microRNAs (miRNAs) that provide a crucial
and pervasive layer of post-transcriptional gene regulation has recently emerged and …

The molecular mechanism for how RISC and microRNAs selectively and reversibly regulate
mRNA translation in response to receptor signaling is unknown but could provide a means …

Many signaling pathways participate in both synaptic plasticity and neuronal degeneration.
While calpains participate in these phenomena, very few studies have evaluated the …