The impact of esophageal oncological surgery on perioperative immune function; implications for adjuvant immune checkpoint inhibition

NE Donlon, M Davern, AD Sheppard… - Frontiers in …, 2022 - frontiersin.org
Background Immune checkpoint inhibitors (ICIs) are being investigated for their role as an
adjunct in the multimodal treatment of esophageal adenocarcinoma (EAC). The most …

Hazard curves for tumor recurrence and tumor-related death following esophagectomy for esophageal cancer

J Lindenmann, M Fediuk, N Fink-Neuboeck… - Cancers, 2020 - mdpi.com
Background: The knowledge of both patterns and risk of relapse following resection for
esophageal cancer is crucial for establishing appropriate surveillance schedules. The aim of …

[HTML][HTML] Moderately differentiated esophageal squamous cell carcinoma has a poor prognosis after neoadjuvant chemoradiotherapy

W He, T Mao, J Yan, X Leng, X Deng… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background Neoadjuvant chemoradiotherapy (NCRT) plus surgery is the standard treatment
for esophageal squamous cell carcinoma (ESCC); however, further analysis is needed to …

The impact of adjuvant therapy on survival after esophagectomy for node-negative esophageal adenocarcinoma

AJ Rucker, V Raman, OK Jawitz, SL Voigt… - Annals of …, 2022 - journals.lww.com
Objective: Determine whether adjuvant chemotherapy is associated with a survival benefit in
high risk T2-4a, pathologically node-negative distal esophageal adenocarcinoma. Summary …

Evaluation of postoperative surveillance strategies for esophago-gastric cancers in the UK and Ireland

S Chidambaram, V Sounderajah… - Diseases of the …, 2022 - academic.oup.com
Esophago-gastric malignancies are associated with a high recurrence rate; yet there is a
lack of evidence to inform guidelines for the standardization and structure of postoperative …

Defining Pathologic Upstaging in cT1b Esophageal Cancer: Should We Consider Neoadjuvant Therapy?

DR Mann, KE Engelhardt, BC Gibney, ME Batten… - Journal of Surgical …, 2024 - Elsevier
Introduction Neoadjuvant chemoradiation therapy (NCRT) for cT1b esophageal cancer is
not recommended despite the risk of pathologic upstaging with increased depth of …

Ongoing challenges with clinical assessment of nodal status in T1 esophageal adenocarcinoma

TB Nobel, A Barbetta, M Hsu, KS Tan, S Sihag… - Journal of the American …, 2019 - Elsevier
Background Endoscopic mucosal resection (EMR) has emerged as an esophageal-
preserving treatment for T1 esophageal adenocarcinoma (EAC); however, only patients with …

[HTML][HTML] Defining low-risk lesions in early-stage esophageal adenocarcinoma

S Sihag, S De La Torre, M Hsu, T Nobel, KS Tan… - The Journal of thoracic …, 2021 - Elsevier
Objective As endoscopic approaches become more widely used to treat early-stage
esophageal cancer, reliably identifying patients with less-aggressive tumors is paramount …

Comparison of local recurrence patterns of postoperative radiotherapy with surgery alone for esophageal carcinoma patients

ZC Xu, BA Su - IJS Oncology, 2021 - journals.lww.com
Background: We analyzed local regional recurrence patterns of thoracic esophageal
carcinoma after three-field lymph node dissection (3-FLD) with and without postoperative …

食管腺癌相关关键基因的筛选及其临床意义.

颜朝阳, 徐同欣, 吴峥, 郭炜… - Chinese Journal of …, 2020 - search.ebscohost.com
目的: 通过TCGA 和GEO 数据库筛选与食管腺癌相关的关键基因, 并分析其生物学功能,
相关信号通路和临床意义. 方法: 综合TCGA 数据库食管腺癌数据和GEO 数据库GSE92396 …