The G· U wobble base pair is a fundamental unit of RNA secondary structure that is present
in nearly every class of RNA from organisms of all three phylogenetic domains. It has …

The genomes of most multicellular organisms contain a new class of introns that have non-
canonical consensus sequences. These minor-class introns occur extremely rarely and are …

It is becoming increasingly clear that RNA is more than a passive carrier of genetic
information. Folded RNA molecules play key roles in almost every aspect of cellular …

Present in the genomes of bacteria and eukaryotic organelles, group II introns are an
ancient class of ribozymes and retroelements that are believed to have been the ancestors …

In this work we review the current knowledge on the prehistory, origins, and evolution of
spliceosomal introns. First, we briefly outline the major features of the different types of …

Group II introns are large, autocatalytic ribozymes that catalyze RNA splicing and
retrotransposition. Splicing by group II introns plays a major role in the metabolism of plants …

The spliceosome, the gigantic molecular machine that performs pre-mRNA splicing in
eukaryotes, contains over 200 different proteins and five RNA molecules. The central role …

Group II introns are large, natural catalytic RNAs or ribozymes that were discovered in
organelles of certain protists, fungi, algae, and plants and more recently also in prokaryotic …

Group II introns are self-splicing, mobile genetic elements that have fundamentally
influenced the organization of terrestrial genomes. These large ribozymes remain important …

Group II introns are large, self-splicing RNAs and mobile genetic elements that provide good
model systems for studies of RNA folding. The structures and mechanistic functions of …