The burden and risks of emerging complications of diabetes mellitus

D Tomic, JE Shaw, DJ Magliano - Nature Reviews Endocrinology, 2022 - nature.com
The traditional complications of diabetes mellitus are well known and continue to pose a
considerable burden on millions of people living with diabetes mellitus. However, advances …

[HTML][HTML] The role of inflammation in diabetes: current concepts and future perspectives

S Tsalamandris, AS Antonopoulos… - European cardiology …, 2019 - ncbi.nlm.nih.gov
Diabetes is a complex metabolic disorder affecting the glucose status of the human body.
Chronic hyperglycaemia related to diabetes is associated with end organ failure. The clinical …

Environmental/lifestyle factors in the pathogenesis and prevention of type 2 diabetes

H Kolb, S Martin - BMC medicine, 2017 - Springer
Background Environmental and lifestyle changes, in addition to the ageing of populations,
are generally believed to account for the rapid global increase in type 2 diabetes prevalence …

Распространенность сахарного диабета 2 типа у взрослого населения России (исследование NATION)

ИИ Дедов, МВ Шестакова, ГР Галстян - Сахарный диабет, 2016 - cyberleninka.ru
Цель. Оценка распространенности сахарного диабета 2 типа (СД2) у взрослого
населения России. Методы. NATION это первое национальное эпидемиологическое …

Pathophysiology of type 1 and type 2 diabetes mellitus: a 90-year perspective

F Zaccardi, DR Webb, T Yates… - Postgraduate medical …, 2016 - academic.oup.com
Diabetes mellitus is a complex metabolic disorder associated with an increased risk of
microvascular and macrovascular disease; its main clinical characteristic is hyperglycaemia …

Body weight considerations in the management of type 2 diabetes

CM Apovian, J Okemah, PM O'Neil - Advances in therapy, 2019 - Springer
Obesity is one of the main risk factors for type 2 diabetes (T2D), representing a major
worldwide health crisis. Modest weight-loss (≥ 5% but< 10%) can minimize and reduce …

FGF21 gene therapy as treatment for obesity and insulin resistance

V Jimenez, C Jambrina, E Casana… - EMBO molecular …, 2018 - embopress.org
Prevalence of type 2 diabetes (T2D) and obesity is increasing worldwide. Currently
available therapies are not suited for all patients in the heterogeneous obese/T2D …

Effect of empagliflozin on ectopic fat stores and myocardial energetics in type 2 diabetes: the EMPACEF study

B Gaborit, P Ancel, AE Abdullah, F Maurice… - Cardiovascular …, 2021 - Springer
Background Empagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that has
demonstrated cardiovascular and renal protection in patients with type 2 diabetes (T2D). We …

[HTML][HTML] Resveratrol and diabetes: from animal to human studies

T Szkudelski, K Szkudelska - … et Biophysica Acta (BBA)-Molecular Basis of …, 2015 - Elsevier
Diabetes mellitus is a serious disease affecting about 5% of people worldwide. Diabetes is
characterized by hyperglycemia and impairment in insulin secretion and/or action …

Dietary polyphenols and gene expression in molecular pathways associated with type 2 diabetes mellitus: A review

GG Kang, N Francis, R Hill, D Waters… - International Journal of …, 2019 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder with various contributing
factors including genetics, epigenetics, environment and lifestyle such as diet. The hallmarks …