Synchronous coordination of calcium-induced calcium release (CICR) across thousands of
calcium release units (CRUs) within the cardiomyocyte is critical for normal excitation …

Calcium (Ca2+) sparks are the elementary events of excitation–contraction coupling, yet
they are not explicitly represented in human ventricular myocyte models. A stochastic …

Calsequestrin Type 2 (CASQ2) is a high-capacity, low-affinity, Ca2+-binding protein
expressed in the sarcoplasmic reticulum (SR) of the cardiac myocyte. Mutations in CASQ2 …

Cardiovascular disease is the leading cause of death worldwide due in a large part to
arrhythmia. In order to understand how calcium dynamics play a role in arrhythmogenesis …

Calcium sparks are the elementary Ca2+ release events in excitation-contraction coupling
that underlie the Ca2+ transient. The frequency-dependent contractile force generated by …

Cardiac alternans is characterized by alternating weak and strong beats of the heart. This
signaling at the cellular level may appear as alternating long and short action potentials …

An example apparatus includes a crossbar array of signal lines and control lines. The
example apparatus also includes an input controller in circuit with the control lines. The input …

According to some embodiments of the present invention there is provided a method for
determining a control action in a control system using a Markov decision process. The …

An integrated circuit device such as a neural network accelerator can be programmed to
select a numerical value based on a multinomial distribution. In various examples, the …

Methods and systems determine at least one production constraint for a material loading
system and a material processing system; estimate an effect of entropy on a cycle time of a …